Zoloft (sertraline) is an antidepressant in a group of drugs called selective serotonin reuptake inhibitors (SSRIs). Sertraline affects chemicals in the brain that may be unbalanced in people with depression, panic, anxiety, or obsessive-compulsive symptoms.

Zoloft is used to treat depression, obsessive-compulsive disorder, panic disorder, anxiety disorders, post-traumatic stress disorder (PTSD), and premenstrual dysphoric disorder (PMDD).

Zoloft may also be used for purposes not listed in this medication guide.

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  • Zoloft
  • Common side effects of Zoloft include insomnia, loose stools, dizziness, drowsiness, tremor, fatigue, diarrhea, dyspepsia, nausea, headache, paresthesia, diaphoresis, decreased libido, delayed ejaculation, ejaculation failure, xerostomia, and anorexia. Other side effects include abdominal pain, agitation, pain, vomiting, hypouricemia, anxiety, and malaise. See below for a comprehensive list of adverse effects.
  • Zoloft (sertraline hydrochloride) tablet, film coated; oral concentrateGeneral dosage information for the active ingredient contained in Zoloft:Sertraline (oral tablet, oral concentrate)Please confirm that the medication forms on the dosage document(s) above are relevant for the specific drug you are intereste