Dexamethasone is a steroid that prevents the release of substances in the body that cause inflammation.

Dexamethasone is used to treat many different conditions such as allergic disorders, skin conditions, ulcerative colitis, arthritis, lupus, psoriasis, or breathing disorders.

Dexamethasone may also be used for purposes not listed in this medication guide.

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  • Baycadron, Dexamethasone Intensol, DexPak 10 Day Taperpak, DexPak 13 DayTaperpak, DexPak 6 DayTaperpak, Dexpak Jr. Taperpak, Zema Pak 10-Day, Zema Pak 13-Day, Zema Pak 6-Day
  • Aggression
    agitation
    anxiety
    blurred vision
    decrease in the amount of urine
    dizziness
    fast, slow, pounding, or irregular heartbeat or pulse
    headache
    irritability
    mental depression
    mood changes
    nervousness
    noisy, rattling breathing
    numbness or tingling in the arms or legs
    pounding in the ears
    shortness of breath
    swelling of the fingers, hands, feet, or lower legs
    trouble thinking, speaking, or walking
    troubled breathing at rest
    weight gain
    Incidence not known:
    Abdominal cramping and/or burning (severe)
    abdominal pain
    backache
    bloody, black, or tarry stools
    cough or hoarseness
    darkening of skin
    decrease in height
    decreased vision
    diarrhea
    dry mouth
    eye pain
    eye tearing
    facial hair growth in females
    fainting
    fatigue
    fever or chills
    flushed, dry skin
    fractures
    fruit-like breath odor
    full or round face, neck, or trunk
    heartburn and/or indigestion (severe and continuous)
    increased hunger
    increased thirst
    increased urination
    loss of appetite
    loss of sexual desire or ability
    lower back or side pain
    menstrual irregularities
    muscle pain or tenderness
    muscle wasting or weakness
    nausea
    pain in back, ribs, arms, or legs
    painful or difficult urination
    skin rash
    sleeplessness
    sweating
    trouble healing
    trouble sleeping
    unexplained weight loss
    unusual tiredness or weakness
    vision changes
    vomiting
    vomiting of material that looks like coffee grounds
  • In cerebral edema, Dexamethasone Sodium Phosphate injection, USP is generally administered initially in a dosage of 10 mg intravenously followed by 4 mg every six hours intramuscularly until the symptoms of cerebral edema subside. Response is usually noted within 12 to 24 hours and dosage may be reduced after two to four days and gradually discontinued over a period of five to seven days. For palliative management of patients with recurrent or inoperable brain tumors, maintenance therapy with either Dexamethasone Sodium Phosphate injection, USP or dexamethasone tablets in a dosage of 2 mg two or three times daily may be effective. Dexamethasone suppression tests Tests for Cushing's syndrome Give 1.0 mg of Dexamethasone USP orally at 11:00 p.m. Blood is drawn for plasma cortisol determination at 8:00 a.m. the following morning. For greater accuracy, give 0.5 mg of Dexamethasone USP orally every 6 hours for 48 hours. Twenty-four hour urine collections are made for determination of 17-hydroxycorticosteroid excretion. Test to distinguish Cushing's syndrome due to pituitary ACTH excess from Cushing's syndrome due to other causes. Give 2.0 mg of Dexamethasone USP orally every 6 hours for 48 hours. Twenty-four hour urine collections are made for determination of 17-hydroxycorticosteroid excretion.