Treating or preventing heartburn, acid indigestion, and sour stomach caused by certain foods and drinks. It may also be used for other conditions as determined by your doctor.

Zantac 75 is a histamine H2-receptor antagonist. It works by blocking the action of histamine in the stomach. This reduces the amount of acid the stomach makes, which helps to relieve symptoms of heartburn, acid indigestion, and sour stomach.

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  • Zantac 75
  • Constipation; diarrhea; headache; nausea; stomach upset.

    Seek medical attention right away if any of these SEVERE side effects occur:
    Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue; unusual hoarseness); change in the amount of urine produced; confusion; dark urine; depression; fast, slow, or irregular heartbeat; fever, chills, or sore throat; hallucinations; severe or persistent headache or stomach pain; unusual bruising or bleeding; yellowing of the eyes or skin.
  • If you are using Zantac 75 to treat symptoms, take it by mouth with or without food. If you are using Zantac 75 to prevent symptoms, take it by mouth 30 to 60 minutes before eating food or drinking beverages that cause your symptoms. Take Zantac 75 with a full glass of water (8 oz/240 mL). If you also take itraconazole or ketoconazole, ask your doctor or pharmacist how to take it with Zantac 75. Do not take other antacids while you are using Zantac 75 without first checking with your doctor. Continue to take Zantac 75 even if you feel well. Do not miss any doses. If you miss a dose of Zantac 75, take it as soon as possible. If it is almost time for your next dose, skip the missed dose and go back to your regular dosing schedule. Do not take 2 doses