Yervoy (ipilimumab) is a cancer medication that interferes with the growth and spread of cancer cells in the body.

Yervoy is used to treat melanoma (skin cancer) that cannot be treated with surgery, or that has spread to other parts of the body.

Yervoy is also used to prevent melanoma from coming back after surgery, including lymph node removal.

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  • Yervoy
  • Get emergency medical help if you have any signs of an allergic reaction to Yervoy: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

    Serious and sometimes fatal reactions may occur during treatment with Yervoy or months after stopping. Contact your doctor right away if you have symptoms such as:

    diarrhea, increased bowel movements, black or bloody stools, stomach tenderness;
    pain in your upper stomach, dark urine, jaundice (yellowing of the skin or eyes), easy bruising or bleeding;
    unusual muscle weakness, numbness or tingling in your hands or feet;
    unusual headaches, feeling cold or tired, weight gain, dizzy spells, mood changes, irritability, confusion;
    mouth sores, skin rash with or without itching, blistering or peeling, skin sores with bleeding; or
    eye pain, or vision problems.
    Call your doctor at once if you have any of these other serious side effects:

    severe stomach pain, bloating, constipation, or vomiting;
    loss of bowel control;
    trouble with daily activities;
    heavy sweating, hot and dry skin, feeling very thirsty or hot;
    little or no urinating;
    severe upper stomach pain spreading to your back, nausea and vomiting, fast heart rate;
    fever, cough, trouble breathing; or
    chest pain, feeling short of breath (even with mild exertion), swelling, rapid weight gain.
    Less serious Yervoy side effects may include:

    tired feeling;
    diarrhea; or
    mild skin rash or itching.
  • ​The recommended dose of YERVOY is 10 mg/kg administered intravenously over 90 minutes every 3 weeks for 4 doses followed by 10 mg/kg every 12 weeks for up to 3 years.