Xigduo XR contains a mix of dapagliflozin and antidiabetic drug. Dapagliflozin and antidiabetic drug square measureoral polygenic disorder medicines that facilitate management glucose levels. Dapagliflozin works by serving to the kidneys get eliminate aldohexose from your blood. antidiabetic drug lowers aldohexose production within the liver and conjointly causes your intestines to soak up less aldohexose.
Xigduo XR is employed beside diet and exercise to treat kind a pair of polygenic disorder. Dapagliflozin isn’t for treating kind one polygenic disorder.
Xigduo XR may additionally be used for functions ex-directory during this medication guide.
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Applies to dapagliflozin / metformin: oral tablet, oral tablet extended release
As well as its needed effects, dapagliflozin / metformin may cause unwanted side effects that require medical attention.
If any of the following side effects occur while taking dapagliflozin / metformin, check with your doctor immediately:
bloody or cloudy urine
change in the color, amount, or odor of vaginal discharge
difficult, burning, or painful urination
frequent urge to urinate
lower back or side pain
Abdominal or stomach discomfort
fast, shallow breathing
general feeling of discomfort
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
muscle pain or cramping
shortness of breath
unusual tiredness or weakness
Incidence not known
cool, pale skin
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
hives, itching, or rash
joint pain, stiffness, or swelling
redness of the skin
swelling of the eyelids, face, lips, hands, or feet
tightness in the chest
Some dapagliflozin / metformin side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:
stuffy or runny nose
body aches or pain
difficulty having a bowel movement (stool)
tender, swollen glands in the neck
Healthcare providers should individualize the starting dose of XIGDUO XR based on the patient’s current treatment. • XIGDUO XR should be taken once daily in the morning with food with gradual dose escalation to reduce the gastrointestinal (GI) side effects due to metformin. • XIGDUO XR tablets must be swallowed whole and never crushed, cut, or chewed. Occasionally, the inactive ingredients of XIGDUO XR will be eliminated in the feces as a soft, hydrated mass that may resemble the original tablet. • Dosing may be adjusted based on effectiveness and tolerability while not exceeding the maximum recommended daily dose of 10 mg dapagliflozin and 2000 mg metformin HCl. • Patients taking an evening dose of metformin XR should skip their last dose before starting XIGDUO XR. • In patients with volume depletion, correcting this condition prior to initiation of XIGDUO XR is recommended.