Diosmiplex works to restore normal blood vessel function.

Diosmiplex is a medical food for people with chronic venous insufficiency, a blood circulation disorder that can cause varicose veins, spider veins, hemorrhoids, blood clots, and other conditions.

Diosmiplex may also be used for purposes not listed in this medication guide.

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  • Vasculera
  • pain, swelling, warmth, or redness; or
    skin changes around a wound or lesion.
    Less serious side effects may include:

    upset stomach;
    mild skin rash;
    leg cramps; or
    swelling in your hands or feet.
  • Diosmiplex is sometimes given once per day. In certain conditions, diosmiplex is given 3 times per day for 4 days and then 2 times per day for 9 days. Follow your doctor's dosing instructions very carefully. It may take up to 8 weeks before your symptoms improve. Keep using the medication as directed and tell your doctor if your symptoms do not improve after 4 weeks of treatment. Contact your doctor if your condition does not improve or if it gets worse after using this medication.