Ursodiol is used for dissolving cholesterol gallstones and treating primary biliary cirrhosis. It also is used for preventing gallstones in obese patients who are losing weight rapidly. It does not dissolve gallstones that are composed of pigment rather than cholesterol. Ursodiol must be used for one or more years, and 50% of patients who have successful dissolution of their gallstones will have the gallstones return within five years. The likelihood of having successful dissolution of gallstones is low if partial dissolution is not seen within 12 months of starting treatment.

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  • Actigall, Urso Forte, Urso 250
  • rash,
    itching,
    nausea,
    vomiting,
    stomach pain,
    back pain,
    constipation,
    diarrhea, and
    hair loss.
  • 13-15mg/kg/day given bid-qid