Treating certain types of seizures. It is also used to treat severe pain of the jaw or cheek caused by a facial nerve problem (trigeminal neuralgia). It may also be used for other conditions as determined by your doctor.
Tegretol XR sustained-release tablets are an anticonvulsant. It works to control seizures by blocking certain nerve impulses in the brain. It works to treat trigeminal neuralgia by altering nerve impulses in certain facial nerves, which relieves pain.
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All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Constipation; dizziness; drowsiness; dry mouth; nausea; unsteadiness; vomiting; weakness.
Seek medical attention right away if any of these SEVERE side effects occur:
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); black, tarry, or bloody stools; burning, numbness, or tingling; calf pain, swelling, or tenderness; change in the amount of urine produced; chest pain; confusion; dark urine; decreased coordination; fainting; fast or irregular heartbeat; fever, chills, or sore throat; hallucinations; joint pain; light-headedness; menstrual changes; new or worsening mental or mood changes (eg, depression, abnormal thoughts, memory problems); new or worsening seizures; pain, tenderness, or unusual swelling in the neck, groin, or under the arms; red or purple spots on your body; red, swollen, blistered, or peeling skin; severe or persistent dizziness or headache; severe or persistent nausea, vomiting, or loss of appetite; shortness of breath; speech problems; stomach pain; sudden, unusual weight gain; suicidal thoughts or actions; swelling of the hands, ankles, or feet; swollen lymph nodes; tremor; trouble concentrating; trouble sleeping; ulcers or sores in the mouth; uncontrolled muscle movements; unusual bruising or bleeding; unusual tiredness or weakness; vision or eye problems (eg, blurred vision); yellowing of the skin or eyes.
Usual Adult Dose for Epilepsy Initial dose: 200 mg orally 2 times a day (immediate and extended release) or 100 mg orally 4 times a day (suspension) Increase dose at weekly intervals by adding up to 200 mg/day using a 2 times a day regimen of extended release or a 3 times a day or 4 times a day regimen of the other formulations. Maintenance dose: 800 to 1200 mg/day. Dosage generally should not exceed 1200 mg/day. However, doses up to 1600 mg/day have been used in rare instances. Use: Epilepsy: -Partial seizures with complex symptomatology (psychomotor, temporal lobe) -Generalized tonic-clonic seizures (grand mal) -Mixed seizure patterns which include the above, or other partial or generalized seizures Usual Adult Dose for Trigeminal Neuralgia -Initial dose: 100 mg orally 2 times a day (immediate or extended release) or 50 mg orally 4 times a day (suspension) -May increase by up to 200 mg per day using increments of 100 mg every 12 hours (immediate or extended release), or 50 mg 4 times a day (suspension), only as needed to achieve freedom from pain. Do not exceed 1200 mg per day. -Maintenance dose: 400 to 800 mg per day Comments: -Some patients may be maintained on as little as 200 mg per day while others may require as much as 1200 mg per day. -At least once every 3 months throughout the treatment period, attempts should be made to reduce the dose to the minimum effective level or to discontinue the drug. Use: -True trigeminal Neuralgia -Beneficial results have also been reported in glossopharyngeal neuralgia Usual Pediatric Dose for Epilepsy Less than 6 years of age: -Initial dose: 10 to 20 mg/kg/day orally in 2 to 3 divided doses (tablets) or 4 divided doses (suspension) -Increase dose at weekly intervals to achieve optimal clinical response administered 3 or 4 times a day. -Maximum dose: 35 mg/kg/day -If satisfactory response not achieved, measure plasma levels to determine if in therapeutic range. -Comments: The manufacturer makes no recommendation regarding the safety of doses above 35 mg/kg/24 hours. 6 to 12 years of age: -Initial dose: 100 mg orally 2 times a day (immediate or extended release tablets) or 50 mg orally 4 times a day (suspension) -Increase dose at weekly intervals in 100 mg per day increments using a 2 times a day regimen of extended release or a 3 times a day or 4 times a day regimen of the other formulations. Maintenance dose: 400 to 800 mg per day Maximum dose: 1000 mg per day Greater than 12 years of age: -Initial dose: 200 mg orally 2 times a day (immediate and extended release) or 100 mg orally 4 times a day (suspension) -Increase dose at weekly intervals in 200 mg per day increments using a 2 times a day regimen of extended release or a 3 times daily to 4 times daily regimen of the other formulations. -Maintenance dose: 800 to 1200 mg per day -Dosage generally should not exceed 1000 mg in children 12 to 15 years and 1200 mg/day in patients older than 15 years. -Doses up to 1600 mg/day have been used in rare instances.