Preventing and controlling bleeding in patients with hemophilia A (factor VIII deficiency), including surgical settings. It may also be used for certain other bleeding conditions.

Recombinate is a man-made clotting factor. It is identical to the naturally occurring protein in the body. It works by increasing the amount of clotting factor VIII in the blood, which helps the blood to clot normally.

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  • Advate, Adynovate, Eloctate with Fc Fusion Protein, Helixate FS, Kogenate FS, Novoeight, Nuwiq, Recombinate, Xyntha
  • Get emergency medical help if you have signs of an allergic reaction: hives; difficulty breathing; feeling light-headed, fainting; swelling of your face, lips, tongue, or throat.

    Stop using recombinant antihemophilic factor and call your doctor at once if you have:

    chest pain;
    easy bruising, increased bleeding episodes; or
    bleeding from a wound or where the medicine was injected.
    Common side effects may include:

    nausea, vomiting, diarrhea;
    headache;
    joint pain;
    sore throat, cough, stuffy nose;
    weakness, feeling tired;
    fever; or
    pain, swelling, itching, or irritation where the injection was given.
  • Use Recombinate as directed by your doctor. Check the label on the medicine for exact dosing instructions. An extra patient leaflet is available with Recombinate. Talk to your pharmacist if you have questions about this information. Recombinate is usually given as an injection at your doctor's office, hospital, or clinic. If you will be using Recombinate at home, a health care provider will teach you how to use it. Be sure you understand how to use Recombinate. Follow the procedures you are taught when you use a dose. Contact your health care provider if you have any questions. Wash your hands before and after use. If Recombinate was stored in the refrigerator, let it reach room temperature before mixing it. Do not heat it. Mix by gently swirling. Do not shake. After mixing, Recombinate must be used within 3 hours. Throw away any unused portion. This product should be colorless to faint yellow after mixing. Do not use Recombinate if it contains particles, is cloudy or discolored, or if the vial is cracked or damaged. When drawing a dose into a syringe, be sure to follow the procedure demonstrated to you by your doctor to prevent contamination of the vial, syringe, or medicine. Never touch the rubber stopper of the vial or the needle of the syringe with your fingers. Carefully check that you have drawn the correct dose before administration. Keep this product, as well as syringes and needles, out of the reach of children and away from pets. Do not reuse needles, syringes, or other materials. Ask your health care provider how to dispose of these materials after use. Follow all local rules for disposal. If you miss a dose of Recombinate, call your doctor to find out what to do.