Quetiapine is an antipsychotic medicine. It works by changing the actions of chemicals in the brain.

Quetiapine is used to treat schizophrenia in adults and children who are at least 13 years old.

Quetiapine is used to treat bipolar disorder (manic depression) in adults and children who are at least 10 years old.

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  • SEROquel, SEROquel XR
  • More common
    cold sweats
    dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
    sleepiness or unusual drowsiness
    Less common
    Black, tarry stools
    blurred vision
    changes in patterns and rhythms of speech
    chest pain
    fever, muscle aches, or sore throat
    inability to move the eyes
    inability to sit still
    increased blinking or spasms of the eyelid
    lip smacking or puckering
    loss of balance control
    mask-like face
    need to keep moving
    painful or difficult urination
    puffing of the cheeks
    rapid or worm-like movements of the tongue
    shakiness in the legs, arms, hands, or feet
    shuffling walk
    slowed movements
    slurred speech
    sores, ulcers, or white spots on the lips or in the mouth
    sticking out of the tongue
    stiffness of the arms or legs
    swelling of the face, arms, hands, feet, or lower legs
    swollen glands
    trembling and shaking of the hands and fingers
    trouble with breathing, speaking, or swallowing
    uncontrolled chewing movements
    uncontrolled movements of the arms and legs
    uncontrolled twisting movements of the neck, trunk, arms, or legs
    unusual bleeding or bruising
    unusual facial expressions
    unusual tiredness or weakness
    Dry, puffy skin
    fast, pounding, or irregular heartbeat
    loss of appetite
    menstrual changes
    unusual secretion of milk (in females)
    weight gain
    Incidence not known
    Aching or discomfort in the lower legs or sensation of crawling in the legs
    painful or prolonged erection of the penis
    puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
    skin rash, hives, itching
    tightness in the chest
    tingling of the hands or feet
    unusual weight gain or loss
    If any of the following symptoms of overdose occur while taking quetiapine, get emergency help immediately:

    Symptoms of overdose
    Convulsions (seizures)
    decreased urine
    dry mouth
    increased thirst
    mood changes
    muscle pain or cramps
    nausea or vomiting
    numbness or tingling in the hands, feet, or lips
    Some quetiapine side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

    More common
    Less common
    Abnormal vision
    acid or sour stomach
    decreased appetite
    decreased strength and energy
    increased appetite
    increased muscle tone
    increased sweating
    increased weight
    stomach discomfort, upset, or pain
    stuffy or runny nose
  • (oral tablet, oral tablet, extended release)