Protopic (tacrolimus)is a topical macrolide immunosuppressant. It works by decreasing cell activity in the body’s immune system which helps to slow down the growth of atopic dermatitis (eczema) on your skin.

Protopic is used to treat severe atopic dermatitis (eczema).

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  • Protopic
  • Incidence not known
    Agitation
    black, tarry stools
    bloody urine
    burning or stinging sensation of the face
    change in size, shape, or color of an existing mole
    coma
    confusion
    convulsions
    decreased frequency or amount of urine
    depression
    fever
    general feeling of illness
    growth or bump on skin
    hostility
    increase in bone pain
    increased blood pressure
    increased thirst
    irritability
    lethargy
    looks very ill
    loss of appetite
    loss of bladder control
    lower back or side pain
    mole that leaks fluid or bleeds
    muscle spasm or jerking of all extremities
    muscle twitching
    nausea
    new mole
    rapid weight gain
    red rash with watery, yellow-colored, or pus filled blisters
    redness of the face
    seizures
    small, red skin lesion, growth, or bump usually on the face, ears, neck, hands, or arms
    sore that will not heal
    spider-like blood vessels on the face
    stupor
    sudden loss of consciousness
    swelling of the face, ankles, lower legs, hands, or fingers
    swollen glands
    thick, yellow to honey-colored crusts
    unusual tiredness or weakness
    vomiting
    weight gain
    weight loss
    yellow skin and eyes
    Some tacrolimus topical side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

    More common
    Cough
    fever
    general aches and pains
    headache
    itching skin—in children
    loss of appetite
    skin burning
    skin flushing in areas of ointment application when drinking alcohol
    sneezing
    weakness
    Less common
    Acid or sour stomach
    acne
    back pain
    belching
    burning, itching, or pain in hairy areas
    chills
    cyst
    flushing
    heartburn
    increased sensitivity to sunlight
    increased skin sensitivity
    indigestion
    itching eyes
    joint pain
    muscle aches or pain
    pain in the eye
    pain or tenderness around the eyes and cheekbones
    pus at root of the hair
    rash
    redness in the eye
    runny nose
    severe skin rash or hives
    skin blisters—in children
    skin tingling
    stomach discomfort, upset, or pain
    stuffy nose
    swelling of the eye, eyelid, or inner lining of the eyelid
    swollen glands
    tightness of the chest
    troubled breathing or wheezing
    watery eyes
  • (tacrolimus) ointment