Primaquine is a medication to treat or prevent malaria, a disease caused by parasites. This medicine works by interfering with the growth of parasites in the body.

Parasites that cause malaria typically enter the body through the bite of a mosquito. Malaria is common in areas such as Africa, South America, and Southern Asia.

Vivax malaria is a form of malaria in which parasites travel from the bloodstream into other cells and tissues of the body. This can cause a second infection (relapse) to occur.

Primaquine is used to prevent malaria from coming back in people who have been infected with the vivax form of this disease.

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  • primaquine
  • More common
    Back, leg, or stomach pains
    dark urine
    fever
    loss of appetite
    pale skin
    unusual tiredness or weakness
    Less common
    Bluish fingernails, lips, or skin
    difficulty breathing
    dizziness or lightheadedness
    Rare
    Sore throat and fever
    Some primaquine side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

    More common
    Cramps
    nausea or vomiting
  • (oral tablet, compounding powder)