Dinoprostone is a prostaglandin, a hormone-like substance that is naturally produced by tissues in the body.

Dinoprostone topical is used in a pregnant woman to relax the muscles of the cervix (opening of the uterus) in preparation for inducing labor at the end of a pregnancy.

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  • Cervidil, Prepidil, Prostin E2
  • Less common or rare
    Fast or slow heartbeat
    hives
    increased pain of the uterus
    pale, cool, blotchy skin on arms or legs
    pressing or painful feeling in chest
    shortness of breath
    swelling of face, inside the nose, and eyelids
    tightness in chest
    trouble in breathing
    weak or absent pulse in arms or legs
    wheezing
    Some dinoprostone topical side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

    More common
    Abdominal or stomach cramps
    diarrhea
    fever
    nausea
    vomiting
    Less common or rare
    Chills or shivering
    constipation
    flushing
    headache
    swelling of the genital area (vulva)
    tender or mildly bloated abdomen or stomach
    This procedure may still result in some effects, which occur after the procedure is completed, that need medical attention. Check with your doctor if any of the following side effects occur while taking dinoprostone topical:

    Chills or shivering (continuing)
    fever (continuing)
    foul-smelling vaginal discharge
    pain in lower abdomen
    unusual increase in bleeding of the uterus
  • (dinoprostone) vaginal gel