Pralidoxime reverses muscle weakness or paralysis caused by a poison or certain drug overdose.

Pralidoxime is used as an antidote to treat poisoning by a chemical or pesticide (insect spray), or by a drug used to treat a muscle disorder.

This medication is not effective as an antidote for all types of pesticide poisonings.

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  • Protopam Chloride
  • More common
    Blurred or double vision
    change in near or distance vision
    difficult or rapid breathing
    difficulty in focusing the eyes
    difficulty with speaking
    dizziness
    fast, pounding, or irregular heartbeat or pulse
    muscle stiffness or weakness
    pain at the injection site (after injection into a muscle)
    Incidence not known
    Deep or fast breathing with dizziness
    numbness of the feet, hands, and around the mouth
    Some pralidoxime side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

    More common
    Drowsiness
    headache
    nausea
  • (intravenous powder for injection)