Piroxicam is a nonsteroidal anti-inflammatory drug (NSAID). This medicine works by reducing substances in the body that cause pain and inflammation.

Piroxicam is used to treat pain or inflammation caused by osteoarthritis or rheumatoid arthritis.

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  • Feldene
  • More common
    Bloating
    bloody or black, tarry stools
    burning upper abdominal or stomach pain
    cloudy urine
    constipation
    decrease in urine output or decrease in urine-concentrating ability
    headache
    heartburn
    indigestion
    itching skin or rash
    loss of appetite
    nausea or vomiting
    pale skin
    severe abdominal or stomach pain, cramping, or burning
    severe and continuing nausea
    swelling
    swelling of the face, fingers, feet, or lower legs
    troubled breathing with exertion
    unusual bleeding or bruising
    unusual tiredness or weakness
    vomiting of blood or material that looks like coffee grounds
    weight changes
    Less common
    Bleeding gums
    blood in the urine
    bloody nose
    blurred vision
    burning feeling in the chest or stomach
    burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
    chest pain
    clay-colored stools
    confusion
    cough or hoarseness
    dark urine
    difficult or labored breathing
    difficult, burning, or painful urination
    difficulty with swallowing
    dilated neck veins
    dizziness
    extreme fatigue
    fainting
    fever or chills
    flushing or redness of the skin
    frequent urge to urinate
    increased sensitivity of the skin to sunlight
    increased thirst
    increased volume of pale, dilute urine
    large, flat, blue, or purplish patches in the skin
    lightheadedness
    lower back or side pain
    nervousness
    noisy breathing
    numbness or tingling in the hands, feet, or lips
    pain or burning in the throat
    peeling of the skin
    pinpoint red or purple spots on the skin
    pounding in the ears
    rapid, shallow breathing
    redness or other discoloration of the skin
    redness, swelling, or soreness of the tongue
    severe sunburn
    slow, fast, pounding, or irregular heartbeat or pulse
    sore throat
    sores, ulcers, or white spots on the lips or tongue or inside the mouth
    stomach upset
    swelling or inflammation of the mouth
    swollen glands
    tenderness in the stomach area
    tightness in the chest
    unpleasant breath odor
    unusually warm skin
    weakness or heaviness of the legs
    yellow eyes or skin
    Rare
    Anxiety
    back or leg pains
    burning, dry, or itching eyes
    cold sweats
    coma
    cracks in the skin
    diarrhea
    discharge or excessive tearing
    dizziness, faintness, or lightheadedness when getting up from a lying or sitting position
    dry mouth
    flushed, dry skin
    fruit-like breath odor
    general body swelling
    general feeling of discomfort or illness
    high fever
    increased hunger
    increased urination
    inflammation of the joints
    irregular, fast or slow, or shallow breathing
    joint pain
    large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
    light-colored stools
    loss of heat from the body
    muscle aches and pains
    nightmares
    no blood pressure
    no breathing
    no pulse
    pain or discomfort in the arms, jaw, back, or neck
    pains in the stomach, side, or abdomen, possibly radiating to the back
    pale or blue lips, fingernails, or skin
    puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
    red skin lesions, often with a purple center
    red, irritated eyes
    redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
    runny nose
    scaly skin
    seeing, hearing, or feeling things that are not there
    seizures
    severe headache
    shakiness
    shivering
    sleepiness
    slurred speech
    sneezing
    sores, welting, or blisters
    stiff neck or back
    stomach pain, continuing
    suddenly sweating
    swollen, painful, or tender lymph glands in the neck, armpit, or groin
    trouble sleeping
    If any of the following symptoms of overdose occur while taking piroxicam, get emergency help immediately:

    Symptoms of overdose
    Agitation
    depression
    hives
    hostility
    irritability
    muscle twitching
    pain or discomfort in the chest, upper stomach, or throat
    rapid weight gain
    stupor
    swelling of the ankles or hands
    unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
    Some piroxicam side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

    More common
    Acid or sour stomach
    belching
    continuing ringing or buzzing or other unexplained noise in the ears
    excess air or gas in the stomach or intestines
    hearing loss
    passing gas
    stomach discomfort or upset
    Less common
    Feeling of constant movement of self or surroundings
    hair loss or thinning of the hair
    lack or loss of strength
    sensation of spinning
    shakiness in the legs, arms, hands, or feet
    trembling or shaking of the hands or feet
    Rare
    Change in hearing
    changes in appetite
    inability to sit still
    mood alterations
    need to keep moving
    restlessness
  • (oral capsule, compounding powder)