Penicillamine is a chelating agent. It attaches to other chemicals in the body, which aids in their removal.

Penicillamine is used to remove excess copper associated with Wilson’s disease. It is also used to reduce cystine in the urine and to treat severe rheumatoid arthritis.

Submit your review

Create your own review

Average rating:  
 0 reviews
  • Cuprimine, Depen
  • More common
    joint pain
    lesions on the face, neck, scalp, and/or trunk
    skin rash, hives, or itching
    swollen and/or painful glands
    ulcers, sores, or white spots on lips or in mouth
    Less common
    Bloody or cloudy urine
    shortness of breath, troubled breathing, tightness in chest, or wheezing
    sore throat and fever with or without chills
    swelling of face, feet, or lower legs
    unusual bleeding or bruising
    unusual tiredness or weakness
    weight gain
    Abdominal or stomach pain (severe)
    blisters on skin
    bloody or black, tarry stools
    chest pain
    coughing or hoarseness
    dark urine
    difficulty in breathing, chewing, talking, or swallowing
    eye pain, blurred or double vision, or any change in vision
    general feeling of discomfort or illness or weakness
    lower back or side pain
    muscle weakness
    painful or difficult urination
    pale stools
    pinpoint red spots on skin
    redness, tenderness, itching, burning, or peeling of skin
    red or irritated eyes
    red, thick, or scaly skin
    ringing or buzzing in the ears
    spitting blood
    yellow eyes or skin
    Some penicillamine side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

    More common
    lessening or loss of sense of taste
    loss of appetite
    nausea or vomiting
    stomach pain (mild)
  • (oral capsule, oral tablet)