Pegvisomant is a man-made protein that is similar to human growth hormone. Pegvisomant binds to the same receptor in the body as growth hormone, and blocks the effects of growth hormone.

Pegvisomant is used to treat acromegaly (a growth disorder caused by too much growth hormone).

Pegvisomant is usually given after other medications, surgery, or radiation have been tried without successful treatment of symptoms.

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  • Somavert
  • More common
    Bleeding, blistering, burning, coldness, or discoloration of skin at site of injection
    bloating or swelling of face, arms, hands, lower legs, or feet
    blurred vision
    chest pain
    chills
    cough
    dizziness
    feeling of pressure
    fever
    headache
    hives
    hoarseness
    infection, inflammation, itching, or lump at site of injection
    nervousness
    lower back or side pain
    painful or difficult urination
    pounding in the ears
    rapid weight gain
    slow or fast heartbeat
    tingling of hands or feet
    unusual weight gain or loss
    Less common
    Thickening of the skin
    Incidence not known
    Abdominal pain or tenderness
    clay colored stools
    dark urine
    decreased appetite
    fever
    itching
    loss of appetite
    nausea and vomiting
    skin rash
    unusual tiredness or weakness
    yellow eyes or skin
    Some pegvisomant side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

    More common
    Accidental injury
    burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
    diarrhea
    general feeling of discomfort or illness
    joint pain
    muscle aches and pains
    pain
    pain or tenderness around eyes and cheekbones
    runny or stuffy nose
    shivering
    shortness of breath or troubled breathing
    sore throat
    sweating
    tightness of chest or wheezing
    trouble sleeping
  • (subcutaneous powder for injection)