Pegasys (peginterferon alfa-2a) is made from human proteins that help the body fight viral infections.

Pegasys is used to treat chronic hepatitis B or hepatitis C in adults, and to treat chronic hepatitis C in children who are at least 5 years old.

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  • Pegasys, Pegasys ProClick Autoinjector
  • More common
    Black, tarry stools
    chills
    cough
    discouragement
    feeling sad or empty
    fever
    irritability
    lack of appetite
    loss of interest or pleasure
    lower back or side pain
    painful or difficult urination
    pale skin
    shortness of breath
    sore throat
    tiredness
    trouble sleeping
    trouble with concentrating
    ulcers, sores, or white spots in the mouth
    unusual bleeding or bruising
    unusual tiredness or weakness
    Less common
    Bone pain
    chest pain or discomfort
    confusion
    constipation
    depressed mood
    dizziness
    dry skin and hair
    fainting
    fast heartbeat
    feeling cold
    hair loss
    headache
    heart murmur
    hives
    hoarseness or husky voice
    lightheadedness
    muscle cramps and stiffness
    pale skin
    rapid, shallow breathing
    slowed heartbeat
    sneezing
    stomach pain
    tightness in the chest
    troubled breathing with exertion
    weight gain
    Some peginterferon alfa-2a side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

    More common
    Back pain
    blistering, crusting, irritation, itching, or reddening of the skin
    cracked, dry, scaly skin
    diarrhea
    dry mouth
    fear
    feeling unusually cold, shivering
    hair loss or thinning of the hair
    muscle or joint pain
    nervousness
    numbness
    pain
    rash
    redness
    scarring
    soreness
    stinging
    stomach pain
    swelling
    tenderness
    tingling
    ulceration
    vomiting
    warmth
    Less common
    Acid or sour stomach
    belching
    blurred vision
    heartburn
    indigestion
    memory problems
    stomach discomfort or upset
    Incidence not known
    Change of hearing
    loss of hearing
  • (peginterferon alfa-2a) injection