Carbinoxamine is used to treat symptoms of seasonal (short-term) or perennial (long-term) allergies, such as sneezing, runny nose, itching, watery eyes, hives, skin rash, itching, or wheezing. It is also used to treat symptoms of allergic rhinitis, allergic conjunctivitis caused by inhaled allergens and foods, or allergic skin reactions. This medicine is an antihistamine.

Carbinoxamine is used with epinephrine to treat severe allergic reactions (anaphylaxis). It is also used to treat allergic reactions to blood or plasma.

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  • Arbinoxa, Carbihist, Carboxine, Histex CT, Histex I/E, Histex PD, Histuss PD, Karbinal ER, Mintex PD, Palgic, Pediatex, Pediox
  • Check with your doctor immediately if any of the following side effects occur:

    Incidence not known
    Blurred vision
    chills
    confusion
    cough
    decrease in the frequency of urination
    decrease in urine volume
    difficult or painful urination
    difficulty in passing urine (dribbling)
    difficulty with swallowing
    dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
    fast, irregular, pounding, or racing heartbeat or pulse
    hives or welts
    itching
    puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
    rash
    redness of the skin
    skin rash
    sweating
    tightness in the chest
    unusual tiredness or weakness
    Get emergency help immediately if any of the following symptoms of overdose occur:

    Symptoms of overdose
    Agitation
    anxiety
    bloating
    convulsions
    diarrhea
    difficulty with sleeping
    disorientation
    dizziness
    drowsiness to profound coma
    dry mouth
    feeling of warmth
    fixed and enlarged pupils
    gas
    headache
    lethargy
    lightheadedness
    loss of appetite
    nausea
    redness of the face, neck, arms, and occasionally, upper chest
    seeing, hearing, or feeling things that are not there
    stomach pain
    tightness of the chest
    trouble breathing
    vomiting
    Some side effects may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

    More common
    Disturbed coordination
    drowsiness
    sleepiness
    Incidence not known
    Back, leg, or stomach pains
    black, tarry stools
    bleeding gums
    blood in the urine or stools
    blurred vision
    burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
    chills
    confusion
    continuing ringing or buzzing or other unexplained noise in the ears
    cough or hoarseness
    dark urine
    difficulty breathing
    difficulty having a bowel movement (stool)
    dizziness or lightheadedness
    double vision
    dry mouth, nose, and throat
    feeling excited
    feeling of constant movement of self or surroundings
    fever with or without chills
    general body swelling
    general feeling of tiredness or weakness
    headache
    hearing loss
    increased sensitivity of the skin to sunlight
    itching
    loss of appetite
    lower back or side pain
    nosebleeds
    pale skin
    pinpoint red spots on the skin
    redness or other discoloration of the skin
    restlessness
    seeing double
    seizures
    sensation of spinning
    severe sunburn
    shakiness in the legs, arms, hands, or feet
    sore throat
    sores, ulcers, or white spots on the lips or in the mouth
    trembling or shaking of the hands or feet
    trouble sleeping
    unusual bleeding or bruising
    weight loss
    yellowing of the eyes or skin
  • Usual Adult Dose for Allergic Rhinitis Tablet (carbinoxamine maleate 4 mg): 1 tablet orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours Tablet, timed-release (carbinoxamine maleate 8 mg): 1 tablet orally every 12 hours Capsule, extended-release (carbinoxamine maleate 2 mg/8 mg): 1 capsule orally every 12 hours, not to exceed 2 capsules in a 24-hour period Solution (carbinoxamine maleate 4 mg/5 mL): 5 mL orally daily as needed; may increase dosage as needed up to a maximum of 24 mg/day in divided doses every 6 to 8 hours Suspension (carbinoxamine maleate-tannate 2 mg-6 mg/5 mL): 5 mL orally every 12 hours Liquid (carbinoxamine maleate 4 mg/5 mL): 5 mL orally 4 times a day Liquid (carbinoxamine maleate 1.5 mg/5 mL): 10 mL orally 4 times a day