Tranylcypromine is a monoamine oxidase inhibitor (MAOI) that works by increasing the levels of certain chemicals in the brain.

Tranylcypromine is used to treat major depressive episode in adults. This medication is usually given after other anti-depressants have been tried without successful treatment of symptoms. Tranylcypromine will not treat bipolar disorder (manic depression).

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  • Parnate
  • Incidence not known
    Absence of or decrease in body movement
    actions that are out of control
    agitation
    anxiety
    black, tarry stools
    bleeding gums
    blood in the urine or stools
    burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
    chest pain
    chills
    coma
    confusion
    confusion about identity, place, and time
    cough or hoarseness
    dark urine
    decrease in frequency of urination
    decrease in urine volume
    depression
    difficulty in passing urine (dribbling)
    dizziness
    dry mouth
    fast, irregular, pounding, or racing heartbeat or pulse
    fever
    fever with or without chills
    general feeling of tiredness or weakness
    headache
    hostility
    hyperventilation
    increased need to urinate
    irregular heartbeats
    irritability
    lethargy
    light-colored stools
    longer than usual time to ejaculation of semen
    loss of bladder control
    lower back or side pain
    muscle twitching
    nausea and vomiting
    nervousness
    painful or difficult urination
    pale skin
    passing urine more often
    pinpoint red spots on the skin
    rapid weight gain
    restlessness
    seizures
    shakiness and unsteady walk
    shortness of breath
    sore throat
    sores, ulcers, or white spots on the lips or in the mouth
    stupor
    sudden jerky movements of the body
    swelling
    swelling of the face, ankles, or hands
    swollen glands
    talking, feeling, and acting with excitement
    trouble with sleeping
    troubled breathing with exertion
    unsteadiness, trembling, or other problems with muscle control or coordination
    unusual bleeding or bruising
    unusual tiredness or weakness
    upper right abdominal pain
    yellow eyes and skin
    Some tranylcypromine side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

    Incidence not known
    Abdominal or stomach pain
    blurred vision
    constipation
    continuing ringing or buzzing or other unexplained noise in the ears
    decreased interest in sexual intercourse
    diarrhea
    drowsiness
    dry mouth
    hair loss or thinning of the hair
    hearing loss
    hives or welts
    inability to have or keep an erection
    itching
    loss in sexual ability, desire, drive, or performance
    loss of appetite
    memory loss
    muscle spasm
    redness of the skin
    skin rash
    sleeplessness
    unable to sleep
    weakness
    weight loss
  • (tranylcypromine sulfate) tablet, film coated