Paricalcitol is a man-made form of vitamin D. Vitamin D is important for the absorption of calcium from the stomach and for the functioning of calcium in the body.

Paricalcitol is used to treat or prevent overactive parathyroid gland (hyperparathyroidism) in people with chronic kidney failure.

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  • Zemplar
  • More common
    Blurred vision
    cough or hoarseness
    difficulty with swallowing
    dizziness
    fever or chills
    headache
    hives
    itching
    lower back or side pain
    nervousness
    pain
    painful or difficult urination
    pounding in the ears
    puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
    shortness of breath
    skin rash
    slow or fast heartbeat
    swelling
    tightness in the chest
    unusual tiredness or weakness
    wheezing
    Less common
    Abdominal or stomach pain
    abnormal growth filled with fluid or semisolid material
    ammonia-like breath odor
    anxiety
    bladder pain
    bloating or swelling of the face, arms, hands, lower legs, or feet
    bloody or cloudy urine
    burning, tingling, numbness or pain in the hands, arms, feet, or legs
    chest pain or discomfort
    cold sweats
    coma
    confusion
    convulsions
    cool, pale skin
    decreased urine
    depression
    dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
    drowsiness
    dry mouth
    fainting
    frequent urge to urinate
    general feeling of discomfort or illness
    increase in heart rate
    increased hunger
    increased thirst
    irregular heartbeat
    joint pain
    lightheadedness
    loss of appetite
    muscle aches and pains
    nausea or vomiting
    nightmares
    numbness or tingling in the hands, feet, or lips
    pain or discomfort in the arms, jaw, back, or neck
    rapid breathing
    rapid weight gain
    runny nose
    sensation of pins and needles
    shakiness
    shivering
    slurred speech
    sneezing
    sore throat
    stabbing pain
    sunken eyes
    sweating
    thirst
    trouble sleeping
    troubled breathing
    unusual weight gain or loss
    weight loss
    wrinkled skin
    Incidence not known
    Large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
    slow or irregular breathing
    If any of the following symptoms of overdose occur while taking paricalcitol, get emergency help immediately:

    Symptoms of overdose
    Abdominal or stomach cramps
    constipation
    depression
    high urine levels of calcium
    incoherent speech
    increased urination
    metallic taste
    muscle cramps in the hands, arms, feet, legs, or face
    muscle weakness
    tremor
    Some paricalcitol side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

    Less common
    Acid or sour stomach
    back pain
    belching
    bloody nose
    bruising
    change in vision
    cough producing mucus
    difficulty with moving
    feeling of constant movement of self or surroundings
    heartburn
    impaired vision
    indigestion
    lack or loss of strength
    large, flat, blue, or purplish patches in the skin
    leg cramps
    muscle pain or stiffness
    pain or tenderness around the eyes and cheekbones
    pain, swelling, or redness in the joints
    sensation of spinning
    sores on the skin
    stomach discomfort, upset, or pain
    stuffy nose
  • (intravenous solution, oral capsule)