Paliperidone is an antipsychotic medicine. It works by changing the effects of chemicals in the brain.

Paliperidone is used to treat schizophrenia in adults and teenagers who are at least 12 years old.

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  • Invega
  • More common
    Difficulty with speaking
    drooling
    fast, pounding, or irregular heartbeat or pulse
    increase in body movements
    loss of balance control
    muscle trembling, jerking, or stiffness
    restlessness
    shuffling walk
    stiffness of the limbs
    twisting movements of the body
    uncontrolled movements, especially of the face, neck, and back
    Less common
    Chest pain
    cold sweats
    confusion
    cough
    difficulty with swallowing
    dizziness
    excessive muscle tone
    fainting
    inability to move the eyes
    increased blinking or spasms of the eyelid
    increased blood pressure
    loss of balance control
    mask-like face
    muscle tension or tightness
    pain in the arms or legs
    slow heartbeat
    slowed movements
    slurred speech
    sticking out tongue when not meaning to
    tic-like (jerky) movements of the head, face, mouth, and neck
    trembling and shaking of the fingers and hands
    tremors
    trouble with breathing, speaking, or swallowing
    uncontrolled twisting movements of the neck, trunk, arms, or legs
    unusual facial expressions
    unusual tiredness or weakness
    Some paliperidone side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

    More common
    Absent, missed, or irregular menstrual periods
    difficulty having a bowel movement (stool)
    fear or nervousness
    headache
    inability to sit still
    nausea
    need to keep moving
    sleepiness or unusual drowsiness
    stopping of menstrual bleeding
    vomiting
    weight gain
    Less common
    Acid or sour stomach
    back pain
    belching
    blurred vision
    changes in appetite
    dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
    dry mouth
    fever
    heartburn
    indigestion
    lack or loss of strength
    muscle aches
    sore throat
    stomach discomfort, upset, or pain
    stuffy or runny nose
    swelling of the breasts or breast soreness in both females and males
    swollen tongue
    unexpected or excess milk flow from breasts
    upper abdominal or stomach pain
  • (oral tablet, extended release, intramuscular suspension, extended release)