Oxaliplatin is a cancer medicine that interferes with the growth and spread of cancer cells in the body.

Oxaliplatin is used together with other cancer medications to treat colon and rectal cancer.

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  • Eloxatin
  • More common
    Abnormal tongue sensation
    black, tarry stools
    bleeding gums
    blistering, peeling, redness, or swelling of the palms of the hands or bottoms of the feet
    blood in the urine or stools
    burning, prickling, itching, or tingling of the skin
    chest pain
    chills
    confusion
    cough
    decreased feeling, or pain in the hands, feet, around the mouth, or throat
    decreased urination
    difficulty performing daily activities such as writing, buttoning, swallowing, or walking
    difficulty with articulating words
    difficulty with breathing
    difficulty with moving
    difficulty with swallowing
    dizziness
    dry mouth
    eye pain
    fainting
    fever
    increase in heart rate
    jaw spasm
    lightheadedness
    muscle pain or stiffness
    numbness
    numbness, pain, tingling, or unusual sensations in the palms of the hands or bottoms of the feet
    pain in the chest, groin, or legs, especially the calves
    pain in the joints
    painful or difficult urination
    pale skin
    pinpoint red spots on the skin
    rapid breathing
    sensation of pins and needles
    severe, sudden headache
    shortness of breath
    slurred speech
    sore throat
    sores, ulcers, or white spots on the lips or in the mouth
    stabbing pain
    sudden loss of coordination
    sudden, severe weakness or numbness in the arm or leg
    sudden, unexplained shortness of breath
    sunken eyes
    swelling
    swelling or inflammation of the mouth
    swollen glands
    thirst
    troubled breathing with exertion
    unusual bleeding or bruising
    unusual tiredness or weakness
    vision changes
    wrinkled skin
    Less common
    Convulsions
    fast heartbeat
    hives
    increased thirst
    irregular heartbeat
    itching
    loss of appetite
    mood changes
    nausea or vomiting
    numbness or tingling in the hands, feet, or lips
    puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
    skin rash
    tightness in the chest
    wheezing
    Incidence not known
    Back, leg, or stomach pains
    blindness
    bloated abdomen
    blue-yellow color blindness
    blurred vision
    changes in patterns and rhythms of speech
    dark urine
    deafness
    decreased vision
    deep breathing
    drowsiness
    electric shock-like sensation that moves down the back and into the legs following a bending movement of the neck
    general body swelling
    increased urination
    large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
    loss of deep tendon reflexes
    muscle tremors
    pain and fullness in the right upper abdomen
    restlessness
    severe constipation
    severe diarrhea
    severe nosebleeds
    severe stomach cramps or tenderness
    severe vomiting
    trouble with speaking
    twitches of the muscle visible under the skin
    weakness of the muscles in your face
    weight gain
    yellow eyes or skin
    If any of the following symptoms of overdose occur while taking oxaliplatin, get emergency help immediately:

    Symptoms of overdose
    Agitation
    coma
    cough or hoarseness
    diarrhea
    disorientation
    involuntary, rapid, or rhythmic movement of the eyes
    lack of coordination
    lack of sensation
    lethargy
    lower back or side pain
    paralysis
    respiratory failure
    seizures
    severe weakness
    slow or irregular heartbeat
    tremors
    vomiting, profuse
    Some oxaliplatin side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

    More common
    Acid or sour stomach
    belching
    body aches or pain
    ear congestion
    feeling unusually cold, shivering
    headache
    heartburn
    indigestion
    loss of voice
    nasal congestion
    runny nose
    sleeplessness
    sneezing
    stomach discomfort, upset, or pain
    trouble sleeping
    unable to sleep
    weight loss
    Less common
    Bad, unusual, or unpleasant (after) taste
    bloated or full feeling
    bloody nose
    burning while urinating
    change in taste
    congestion
    cracked lips
    dryness or soreness of the throat
    excess air or gas in stomach or intestines
    feeling of warmth
    hair loss
    passing gas
    rapid weight gain
    redness of the face, neck, arms, and occasionally upper chest
    tender, swollen glands in the neck
    thinning of the hair
    unusual tearing of the eyes
    voice changes
  • (intravenous solution, intravenous powder for injection)