Ofloxacin is an antibiotic in a group of drugs called fluoroquinolones (flor-o-KWIN-o-lones). Ofloxacin fights bacteria in the body.

Ofloxacin is used to treat bacterial infections of the skin, lungs, prostate, or urinary tract (bladder and kidneys). Ofloxacin is also used to treat pelvic inflammatory disease and Chlamydia and/or gonorrhea.

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  • Floxin, Floxin I.V
  • Less common
    Abdominal or stomach pain
    black, tarry stools
    bleeding gums
    blood in the urine or stools
    blurred vision
    body aches or pain
    chest pain
    cloudy urine
    cold sweats
    cool, pale skin
    dry mouth
    dryness or soreness of the throat
    eye pain
    fast heartbeat
    flushed, dry skin
    fruit-like breath odor
    general feeling of illness
    increased hunger
    increased thirst
    increased urination
    lower back or side pain
    painful or difficult urination
    pale skin
    pinpoint red spots on the skin
    pus in the urine
    runny nose
    shortness of breath
    slurred speech
    sore throat
    sores, ulcers, or white spots on the lips or in the mouth
    swollen glands
    tender, swollen glands in the neck
    trouble with swallowing
    troubled breathing with exertion
    unexplained weight loss
    unusual bleeding or bruising
    unusual tiredness or weakness
    voice changes
    Burning while urinating
    burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
    change in color vision
    continuing ringing or buzzing or other unexplained noise in the ears
    decrease in frequency of urination
    decrease in urine volume
    decreased hearing or any change in hearing
    difficult or painful urination
    difficulty in passing urine (dribbling)
    difficulty seeing at night
    difficulty with moving
    dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
    false or unusual sense of well-being
    fast, irregular, pounding, or racing heartbeat or pulse
    fear or nervousness
    feeling of constant movement of self or surroundings
    feeling of warmth or heat
    feeling sad or empty
    flushing or redness of the skin, especially on the face and neck
    hearing loss
    hives or welts
    increased need to urinate
    increased sensitivity of the eyes to sunlight
    increased sweating
    joint pain
    lack of appetite
    large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
    loss of bladder control
    loss of interest or pleasure
    muscle aching or cramping
    muscle pains or stiffness
    muscle spasm or jerking of all extremities
    no blood pressure or pulse
    no breathing
    passing urine more often
    pounding in the ears
    redness, soreness, or itching skin
    seeing, hearing, or feeling things that are not there
    sensation of spinning
    shakiness in the legs, arms, hands, or feet
    skin rash
    slow or fast heartbeat
    sores, welting, or blisters
    stopping of the heart
    sudden loss of consciousness
    swollen joints
    trembling or shaking of the hands or feet
    trouble concentrating
    trouble performing routine tasks
    trouble sleeping
    Incidence not known
    Abdominal or stomach tenderness
    actions that are out of control
    back, leg, or stomach pains
    blistering, peeling, or loosening of the skin
    blue lips and fingernails
    burning, dry, or itching eyes
    changes in behavior
    confusion about identity, place, and time
    coughing that sometimes produces a pink frothy sputum
    coughing up blood
    cracks in the skin
    dark-colored urine
    darkening of the skin
    delusions of persecution, mistrust, suspiciousness, and/or combativeness
    diarrhea, watery and severe, which may also be bloody
    difficulty with breathing, chewing, or talking
    difficulty with speaking
    difficulty with swallowing
    discharge or excessive tearing
    double vision
    drooping eyelids
    feeling of discomfort
    general body swelling
    high fever
    increased blood pressure
    increased menstrual flow or vaginal bleeding
    increased sensitivity of the skin to sunlight
    increased sweating
    inflammation of the joints
    irregular heartbeats
    irregular or slow heart rate
    itching of the vagina or outside the genitals
    loss of ability to use or understand speech or language
    loss of appetite
    loss of balance control
    loss of heat from the body
    mental depression
    mood or mental changes
    muscle weakness
    noisy breathing
    numbness of the hands
    pain during sexual intercourse
    pain in the ankles or knees
    pain, inflammation, or swelling in the calves, shoulders, or hands
    painful, red lumps under the skin, mostly on the legs
    prolonged bleeding from cuts
    puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
    quick to react or overreact emotionally
    rapidly changing moods
    red or black, tarry stools
    red or dark brown urine
    red skin lesions, often with a purple center
    red, irritated eyes
    red, swollen skin
    redness or other discoloration of the skin
    redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
    scaly skin
    severe abdominal pain, cramping, or burning
    severe sunburn
    severe tiredness
    shuffling walk
    stiffness of the limbs
    stomach pain, continuing
    swelling of the face, fingers, or lower legs
    swollen lymph glands
    talking, feeling, and acting with excitement
    thick, white, curd-like vaginal discharge without odor or with mild odor
    thoughts of killing oneself
    twisting movements of the body
    uncontrolled eye movements
    uncontrolled movements, especially of the face, neck, and back
    unexplained bleeding or bruising
    unpleasant breath odor
    unsteadiness or awkwardness
    unusual behavior, such as disorientation to time or place, failure to recognize people, hyperactivity, or restlessness, especially in children using 2% cyclopentolate
    unusual weight loss
    upper right abdominal pain
    vomiting of blood or material that looks like coffee grounds
    weakness in the arms, hands, legs, or feet
    weight gain
    yellowing of the eyes or skin
    Some ofloxacin side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

    More common
    unable to sleep
    Less common
    Change in taste
    excess air or gas in the stomach or intestines
    full feeling
    loss of taste
    passing gas
    runny nose
  • (oral tablet, intravenous solution)
  • Bacterial Infection

    Treating certain bacterial infections. It may be used in combination with other medicines to treat acne or certain amoeba infections. It may be used to prevent certain types of malaria in travelers who will be visiting malaria-infected areas for less than 4 months. It may also be used to prevent or slow the progression of anthrax after exposure. Doryx delayed-release capsules are a tetracycline antibiotic. It works by slowing the growth of bacteria. Slowing the bacteria's growth allows the body's immune system to destroy the bacteria.