Mitoxantrone is a cancer medication that interferes with the growth and spread of cancer cells in the body.

Mitoxantrone is used to treat prostate cancer and certain types of leukemia.

Mitoxantrone is also used to treat the symptoms of relapsing multiple sclerosis. This medication will not cure multiple sclerosis.

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  • Novantrone
  • More common
    Black, tarry stools
    bladder pain
    bloody or cloudy urine
    cough or shortness of breath
    difficult, burning, or painful urination
    dizziness
    fainting
    fast, slow, or irregular heartbeat
    frequent urge to urinate
    lower back or side pain
    pale skin
    stomach pain
    swelling or inflammation of the mouth
    troubled breathing with exertion
    ulcers, sores, or white spots in the mouth
    unusual bleeding or bruising
    unusual tiredness or weakness
    Less common
    Blood in the urine or stools
    decrease in urination
    fever or chills
    pinpoint red spots on the skin
    seizures
    sore, red eyes
    swelling of the feet and lower legs
    yellow eyes or skin
    Rare
    Blue skin at the place of injection
    pain or redness at the place of injection
    skin rash
    Some mitoxantrone side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

    More common
    Absent, missed, or irregular menstrual periods
    back pain
    body aches or pains
    congestion
    constipation
    diarrhea
    dryness or soreness of the throat
    hair loss
    headache
    longer or heavier menstrual periods
    nausea or vomiting
    oral bleeding
    pain or tenderness around the eyes and cheekbones
    runny nose
    sneezing
    stopping of menstrual bleeding
    stuffy nose
    tender, swollen glands in the neck
    thinning of the hair
  • (mitoxantrone hydrochloride) injection, solution