Treating breast cancer that has spread to other sites in the body. It is also used along with other medicines to treat other types of breast cancer. It is used in women who are at high risk for breast cancer and in women with DCIS (after surgery and radiation) to decrease the risk of developing breast cancer. It may also be used for other conditions as determined by your doctor.

Nolvadex is an antiestrogen. It works by blocking the effect of estrogen on certain tumors. This may prevent the growth of tumors that are activated by estrogen.

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  • Nolvadex
  • Less common or rare
    Anxiety
    blistering, peeling, or loosening of the skin and mucous membranes
    blurred vision
    cataracts in the eyes or other eye problems
    change in vaginal discharge
    chest pain
    chills
    confusion
    cough
    dizziness
    fainting
    fast heartbeat
    fever
    hoarseness
    lightheadedness
    lower back or side pain
    pain or feeling of pressure in the pelvis
    pain or swelling in the legs
    pain, redness, or swelling in your arm or leg
    painful or difficult urination
    rapid shallow breathing
    shortness of breath or trouble with breathing
    skin rash or itching over the entire body
    sweating
    weakness or sleepiness
    wheezing
    vaginal bleeding
    yellow eyes or skin
    Incidence not known
    Bloating
    constipation
    darkened urine
    diarrhea
    difficulty with breathing
    indigestion
    itching
    joint or muscle pain
    large, hard skin blisters
    large hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, and sex organs
    loss of appetite
    nausea
    pain in the stomach or side, possibly radiating to the back
    red, irritated eyes
    red skin lesions, often with a purple center
    sore throat
    sores, ulcers or white spots in the mouth or on the lips
    unusual tiredness or weakness
    vomiting
    Some tamoxifen side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

    More common
    Absent, missed, or irregular periods
    decrease in the amount of urine
    feeling of warmth
    menstrual changes
    noisy, rattling breathing
    redness of the face, neck, arms and occasionally, upper chest
    skin changes
    stopping of menstrual bleeding
    swelling of the fingers, hands, feet, or lower legs
    troubled breathing at rest
    weight gain or loss
    white or brownish vaginal discharge
    Less common or rare
    Abdominal or stomach cramps
    black, tarry stools
    bleeding gums
    blood in the urine or stools
    bluish color changes in skin color
    bone pain
    decreased interest in sexual intercourse
    discouragement
    feeling sad or empty
    hair loss or thinning of the hair
    headache
    inability to have or keep an erection
    irritability
    itching in the genital area
    loss of interest or pleasure
    loss in sexual ability, desire, drive, or performance
    nausea or vomiting (mild)
    pain
    pinpoint red spots on the skin
    skin rash or dryness
    stomach or pelvic discomfort, aching, or heaviness
    swelling
    trouble concentrating
    trouble with sleeping
    unusual bleeding or bruising
  • (tamoxifen citrate) tablets