Nilotinib is a cancer medication that interferes with the growth and spread of cancer cells in the body.

Nilotinib is used to treat a type of blood cancer called Philadelphia chromosome positive chronic myeloid leukemia (CML).

Nilotinib is usually given after other medications have been tried without success.

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  • Tasigna
  • More common
    Abdominal or stomach pain or tenderness
    black, tarry stools
    bleeding gums
    blood in the urine or stools
    blurred vision
    bone pain
    clay colored stools
    cough or hoarseness
    dark urine
    decreased appetite
    difficult or labored breathing
    dry mouth
    fever or chills
    flushed, dry skin
    fruit-like breath odor
    increased hunger
    increased thirst
    increased urination
    irregular heartbeat, recurrent
    loss of appetite
    lower back or side pain
    muscle aches, cramps, or pain
    nausea and vomiting
    no blood pressure
    no breathing
    no pulse
    numbness, tingling, pain, or weakness in the hands or feet
    painful or difficult urination
    pale skin
    pinpoint red spots on the skin
    skin rash or itching
    sore throat
    stuffy or runny nose
    swelling of the hands, ankles, feet, or lower legs
    tightness in the chest
    troubled breathing with exertion
    ulcers, sores, or white spots in the mouth
    unexplained weight loss
    unusual bleeding or bruising
    unusual tiredness or weakness
    weakness and heaviness of the legs
    yellow eyes or skin
    Less common
    decreased urine output
    fast heartbeat
    muscle cramps in the hands, arms, feet, legs, or face
    numbness and tingling around the mouth, fingertips, or lips
    rapid weight gain
    Less common or rare
    Bladder pain
    bloody or cloudy urine
    body aches or pain
    cough producing mucus
    depressed mood
    difficult, burning, or painful urination
    dry skin and hair
    ear congestion
    feeling cold
    frequent urge to urinate
    hair loss
    loss of voice
    muscle stiffness
    pain or tenderness around the eyes and cheekbones
    sensitivity to heat
    slowed heartbeat
    swelling or puffiness of the face
    tender, swollen glands in the neck
    trouble sleeping
    trouble swallowing
    weight changes
    white patches in the mouth or throat or on the tongue
    white patches with diaper rash
    Incidence not known
    Pain or swelling of the treated skin
    rapid, shallow breathing
    Some nilotinib side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

    More common
    Back pain
    burning, itching, and pain in hairy areas
    difficulty with moving
    lack or loss of strength
    muscle spasms
    pain in the arms or legs
    pain in the joints
    pus at the root of the hair
    swollen joints
  • (oral capsule)