Niaspan ER extended release works by reducing LDL (“bad”) cholesterol and triglycerides and increasing HDL (“good”) cholesterol. Niaspan contains niacin, also called nicotinic acid, a B vitamin (vitamin B3). It occurs naturally in plants and animals and is present in many multiple vitamin supplements.

Niaspan ER is used to lower cholesterol and triglycerides (types of fat) in the blood. It is also used to lower the risk of heart attack in people with high cholesterol who have already had a heart attack. It is sometimes used to treat coronary artery disease (also called atherosclerosis).

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  • B-3-50, B3-500-Gr, Niacin SR, Niacor, Niaspan ER, Slo-Niacin
  • Less common
    Darkening of urine
    light gray-colored stools
    loss of appetite
    severe stomach pain
    yellow eyes or skin
    Some niacin side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

    Less common
    Abdominal or stomach pain
    cough
    diarrhea
    feeling of warmth
    flushing or redness of the skin, especially on the face and neck
    headache
    nausea or vomiting
    rash or itching
    runny nose
    sneezing
    stuffy nose
    Incidence not known
    Dizziness or faintness
    dryness of the skin
    fever
    frequent urination
    joint pain
    muscle aching or cramping
    side, lower back, or stomach pain
    swelling of the feet or lower legs
    unusual thirst
    unusual tiredness or weakness
    unusually fast, slow, or irregular heartbeat
  • (niacin) tablet, film coated, extended release