In deciding to use a medicine, the risks of taking the medicine must be weighed against the good it will do. This is a decision you and your doctor will make. For this medicine, the following should be considered:

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  • Cobal, Cobolin-M, Depo-Cobolin, LA-12, Neuroforte-R, Vita #12, Vitabee 12
  • Abdominal or stomach pain
    bleeding from the gums or nose
    blue lips and fingernails
    chest pain
    coughing that sometimes produces a pink frothy sputum
    decreased urine output
    difficult, fast, noisy breathing, sometimes with wheezing
    difficulty with swallowing
    dilated neck veins
    extreme fatigue
    eye pain
    fast heartbeat
    hives, itching, or skin rash
    increased sweating
    irregular breathing
    irregular heartbeat
    pale skin
    puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
    ringing in the ears
    swelling of the face, fingers, feet, or lower legs
    tightness in the chest
    unusual tiredness or weakness
    weight gain
  • Initial dose: 1000 mcg intramuscularly once a day for 7 days. If there is clinical improvement and a reticulocyte response, 1000 mcg intramuscularly once every other day for 7 days, then once every 3 to 4 days for another 2 to 3 weeks is recommended. Most patients require monthly injections of 100 to 1000 mcg intramuscularly for life.