Treating myasthenia gravis. It may also be used for other conditions as determined by your doctor.

Neostigmine is a cholinesterase inhibitor. It works by improving the transmission of nerve impulses in muscles so that the muscles are better able to work.

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  • Prostigmin
  • More common
    Twitches of the muscle visible under the skin
    Incidence not known
    Blurred or loss of vision
    changes in patterns and rhythms of speech
    chest pain or discomfort
    confusion
    cough
    difficult or labored breathing
    difficulty in moving
    difficulty swallowing
    disturbed color perception
    dizziness, faintness, or lightheadedness when getting up from a lying or sitting position suddenly
    double vision
    fast, pounding, or irregular heartbeat or pulse
    halos around lights
    hives
    irregular, fast or slow, or shallow breathing
    itching
    lightheadedness, dizziness, or fainting
    loss of consciousness
    muscle cramps and spasms
    muscle pain or stiffness
    night blindness
    no blood pressure or pulse
    noisy breathing
    overbright appearance of lights
    pain in joints
    pale or blue lips, fingernails, or skin
    puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
    seizures
    shortness of breath
    skin rash
    slow or irregular heartbeat
    slurred speech
    stopping of heart
    sweating
    tightness in chest
    trouble in speaking
    tunnel vision
    unconsciousness
    unusual tiredness or weakness
    wheezing
    If any of the following symptoms of overdose occur while taking neostigmine, get emergency help immediately:

    Symptoms of Overdose
    Constipation
    decreased sexual ability
    difficult urination
    dry mouth
    enlarged pupils
    muscle weakness
    Some neostigmine side effects may not need any medical attention. As your body gets used to the medicine these side effects may disappear. Your health care professional may be able to help you prevent or reduce these side effects, but do check with them if any of the following side effects continue, or if you are concerned about them:

    More common
    Increased watering of mouth
    Incidence not known
    Bloated
    constricted, pinpoint, or small pupils (black part of eye)
    diarrhea
    drowsiness
    excess air or gas in stomach or intestines
    feeling of warmth
    full feeling
    headache
    increase in mucous from lungs
    increased need to urinate
    increased sweating
    nausea
    passing gas
    passing urine more often
    redness of skin
    redness of the face, neck, arms and occasionally, upper chest
    skin rash
    stomach cramps
    vomiting
  • Injection