This medication guide provides information about the Korlym brand of mifepristone. Mifeprex is another brand of mifepristone that is not covered in this medication guide.

Korlym blocks the actions of a hormone called cortisol, which can reduce certain side effects caused by excess cortisol in the body.

Korlym is used to treat high blood sugar (hyperglycemia) in adults with Cushing’s syndrome who also have type 2 diabetes or glucose intolerance.

Korlym should not be used to treat type 2 diabetes that is not related to Cushing’s syndrome.

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  • Korlym
  • Less common
    Excessively heavy vaginal bleeding
    unusual tiredness or weakness
    Incidence not known
    Chest pain or discomfort
    confusion
    cough or hoarseness
    fast, weak pulse
    fever or chills
    lower back or side pain
    pain or discomfort in the arms, jaw, back, or neck
    painful or difficult urination
    pale, cold, or clammy skin
    shortness of breath
    sudden increase in stomach or shoulder pain
    sweating
    unusual or large amount of vaginal bleeding
    Some of the side effects that can occur with mifepristone may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common
    Abdominal or stomach pain or uterine cramping
    back pain
    diarrhea
    dizziness
    headache
    nausea or vomiting
    Less common
    Acid or sour stomach
    anxiety
    belching
    cough
    fainting or lightheadedness when getting up from a lying or sitting position
    fever
    flu-like symptoms
    headache
    heartburn
    increased clear or white vaginal discharge
    indigestion
    itching of the vagina or genital area
    lack or loss of strength
    pain during sexual intercourse
    pain or tenderness around the eyes and cheekbones
    pale skin
    shaking chills
    shortness of breath or troubled breathing
    sleeplessness or trouble sleeping
    stomach discomfort, upset, or pain
    stuffy or runny nose
    tightness of the chest or wheezing
    troubled breathing, exertional
    unusual bleeding or bruising
  • (oral tablet)