Metreleptin is used together with diet to treat complications caused by leptin deficiency in people who have lipodystrophy (also called fat redistribution). Lipodystrophy (LIP-oh-DIS-tro-fee) is a problem with the way the body stores fat.
Metreleptin is not for use in people who have lipodystrophy caused by taking medicine to treat HIV or AIDS.
body aches or pain
burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
chills or fever
unusual tiredness or weakness
pains in the stomach, side, or abdomen, possibly radiating to the back
Some of the side effects that can occur with metreleptin may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:
earache or pain in the ear
muscle pain or stiffness
pain in the joints
(subcutaneous powder for injection)