Metreleptin is used together with diet to treat complications caused by leptin deficiency in people who have lipodystrophy (also called fat redistribution). Lipodystrophy (LIP-oh-DIS-tro-fee) is a problem with the way the body stores fat.

Metreleptin is not for use in people who have lipodystrophy caused by taking medicine to treat HIV or AIDS.

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  • Myalept
  • More common
    Anxiety
    blurred vision
    body aches or pain
    burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
    chills or fever
    cold sweats
    confusion
    dizziness
    fast heartbeat
    headache
    increased hunger
    nausea
    nervousness
    shakiness
    sore throat
    unusual tiredness or weakness
    Less common
    Bloating
    pains in the stomach, side, or abdomen, possibly radiating to the back
    vomiting
    Some of the side effects that can occur with metreleptin may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common
    Back pain
    diarrhea
    ear drainage
    earache or pain in the ear
    muscle pain or stiffness
    pain in the joints
    weight loss
  • (subcutaneous powder for injection)