Testing hypothalamus and pituitary function.

Metopirone is a diagnostic aid. It works by blocking the body’s natural production of cortisol and corticosterone, which increases the production of corticotropin (ACTH). This helps to test the function of the hypothalamus and pituitary gland.

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  • Metopirone
  • Less common
    Skin rash
    Rare (usually with long-term use)
    Enlargement of clitoris
    muscle cramps or pain
    sore throat or fever
    swelling of feet or lower legs
    unusual bleeding or bruising
    unusual tiredness or weakness
    weight gain (rapid)
    Symptoms of overdose
    Abdominal or stomach pain (severe)
    confusion
    decrease in consciousness
    diarrhea (severe)
    nausea (severe)
    nervousness
    unusual thirst
    vomiting (severe)
    weakness (sudden)
    Some of the side effects that can occur with metyrapone may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common
    Dizziness
    drowsiness
    headache
    lightheadedness
    nausea
    Rare
    Confusion or mental slowing
    excessive hair growth
    greater-than-normal loss of scalp hair
    increased sweating
    loss of appetite
    upper abdominal or stomach pain
    vomiting
    worsening of acne
  • (metyrapone) capsule, gelatin coated