Methylergonovine is in a group of drugs called ergot alkaloids. It affects the smooth muscle of a woman’s uterus, improving the muscle tone as well as the strength and timing of uterine contractions.

Methylergonovine is used just after a baby is born, to help deliver the placenta (also called the “afterbirth”). It is also used to help control bleeding and to improve muscle tone in the uterus after childbirth.

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  • Methergine
  • More common
    Abdominal pain
    headache
    increased blood pressure
    Rare
    Blood in the urine
    change in skin color
    chest pain or discomfort
    difficult or labored breathing
    difficulty with swallowing
    dizziness
    fast, pounding, or irregular heartbeat or pulse
    hives
    lightheadedness, dizziness, or fainting
    pain or discomfort in the arms, jaw, back, or neck
    pain, tenderness, or swelling of the foot or leg
    puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
    slow or fast heartbeat
    skin rash
    sweating
    vomiting
    Incidence not known
    Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
    confusion
    dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
    fainting
    inability to speak
    seizures
    severe or sudden headache
    slurred speech
    temporary blindness
    weakness in the arm or leg on one side of the body, sudden and severe
    Some of the side effects that can occur with methylergonovine may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    Rare
    Continuous ringing or buzzing or other unexplained noise in the ears
    cramps in the legs
    diarrhea
    foul taste
    increased sweating
    nausea
    stuffy nose
  • (methylergonovine maleate) tablet. injection