Memantine reduces the actions of chemicals in the brain that may contribute to the symptoms of Alzheimer’s disease.

Memantine is used to treat moderate to severe dementia of the Alzheimer’s type.

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  • Namenda, Namenda XR
  • Less common
    Bloating or swelling of the face, arms, hands, lower legs, or feet
    blurred vision
    dizziness
    headache
    nervousness
    pounding in the ears
    rapid weight gain
    slow or fast heartbeat
    tingling of the hands or feet
    unusual weight gain or loss
    Incidence not known
    Abdominal or stomach pain
    agitation
    black, tarry stools
    bleeding gums
    blistering, peeling, or loosening of the skin
    blood in the urine or stools
    chest pain
    coma
    constipation
    continuing vomiting
    convulsions
    dark-colored urine
    decreased urine output
    depression
    fainting
    fast, pounding, or irregular heartbeat or pulse
    general feeling of tiredness or weakness
    high fever
    high or low blood pressure
    hostility
    increased sweating
    indigestion
    infection from breathing foreign substances into the lungs
    itching
    lethargy
    light-colored stools
    lip smacking or puckering
    loss of consciousness
    muscle twitching
    no blood pressure
    no breathing
    no pulse
    numbness or tingling in the face, arms, or legs
    pain in the stomach, side, or abdomen, possibly radiating to the back
    pain or swelling in the arms or legs without any injury
    pain, tension, and weakness upon walking that subsides during periods of rest
    pinpoint red spots on the skin
    pounding, slow heartbeat
    puffing of the cheeks
    rapid or worm-like movements of the tongue
    rapid weight gain
    recurrent fainting
    red irritated eyes
    red skin lesions, often with a purple center
    seizures
    severe constipation
    severe headache
    severe muscle stiffness
    severe vomiting
    sores, ulcers, or white spots in the mouth or on the lips
    stupor
    sudden severe weakness
    swelling of the face, ankles, or hands
    total body jerking
    trouble with speaking or walking
    troubled breathing
    twitching, twisting, or uncontrolled repetitive movements of the tongue, lips, face, arms, or legs
    uncontrolled chewing movements
    unusual bleeding or bruising
    unusually pale skin
    vomiting
    yellow eyes and skin
    Some of the side effects that can occur with memantine may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common
    Confusion
    Less common
    Anxiety
    back pain
    bladder pain
    bloody or cloudy urine
    change in walking and balance
    chills
    clumsiness or unsteadiness
    cough producing mucus
    coughing
    diarrhea
    difficult, burning, or painful urination
    difficulty with breathing
    difficulty with moving
    discouragement
    dry mouth
    fear
    feeling sad or empty
    fever
    frequent urge to urinate
    general feeling of discomfort or illness
    hyperventilation
    insomnia
    irritability
    joint pain
    loss of appetite
    loss of bladder control
    loss of interest or pleasure
    lower back or side pain
    muscle pain or stiffness
    nausea
    nervousness
    pain
    pain in the joints
    restlessness
    seeing, hearing, or feeling things that are not there
    shortness of breath
    sleepiness or unusual drowsiness
    sore throat
    tightness in the chest
    tiredness
    trouble with concentrating
    trouble with sleeping
    unusual tiredness or weakness
    vomiting
    wheezing
    Incidence not known
    Burning feeling in the chest or stomach
    burning, numbness, pain, or tingling in all fingers except smallest finger
    cold sweats
    cool pale skin
    decreased interest in sexual intercourse
    difficulty with swallowing
    general feeling of discomfort or illness
    heartburn
    inability to have or keep an erection
    increased hunger
    large amounts of fat in the blood
    loss in sexual ability, desire, drive, or performance
    nightmares
    shakiness
    slurred speech
    stomach cramps
    stomach upset
    tenderness in the stomach area
    watery or bloody diarrhea
  • (oral tablet, oral kit, oral solution, oral capsule, extended release)