Mechlorethamine is used to treat the symptoms of several types of cancer. Mechlorethamine treats only the symptoms of cancer but does not treat the cancer itself.

Mechlorethamine is also sometimes injected into body spaces around the heart, lungs, or stomach to treat fluid retention in these areas caused by cancer.

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  • Mustargen
  • Less common
    Black, tarry stools
    blood in urine or stools
    cough or hoarseness
    fever or chills
    lower back or side pain
    pain or redness at place of injection
    painful or difficult urination
    pinpoint red spots on skin
    unusual bleeding or bruising
    Rare
    Shortness of breath, itching, or wheezing
    If any of the following side effects occur while taking mechlorethamine, check with your doctor or nurse as soon as possible:

    More common
    Missing menstrual periods
    painful rash
    Less common
    Dizziness
    joint pain
    loss of hearing
    ringing in ears
    swelling of feet or lower legs
    Rare
    Numbness, tingling, or burning of fingers, toes, or face
    sores in mouth and on lips
    yellow eyes or skin
    Some of the side effects that can occur with mechlorethamine may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common
    Nausea and vomiting (usually lasts only 8 to 24 hours)
    Less common
    Confusion
    diarrhea
    drowsiness
    headache
    loss of appetite
    metallic taste
    weakness
    This medicine may cause a temporary loss of hair in some people. After treatment with mechlorethamine has ended, normal hair growth should return.

    After you stop taking this drug, it is possible that you may still experience side effects that need medical attention. If you notice any of the following side effects check with your doctor immediately:

    Black, tarry stools
    blood in urine or stools
    cough or hoarseness
    fever or chills
    lower back or side pain
    painful or difficult urination
    pinpoint red spots on skin
    unusual bleeding or bruising
  • (injectable powder for injection)