Mecasermin is a man-made form of insulin-like growth factor-1 (IGF-1), a substance that is normally produced in the body. IGF-1 is important for the growth of bones and muscles.

Mecasermin is used to treat growth failure in children whose bodies do not make enough IGF-1.

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  • Increlex
  • More common
    Anxiety
    bluish skin color of the fingertips
    blurred vision
    breathlessness
    chest pain
    chills
    cold sweats
    coma
    confusion
    cool, pale skin
    depression
    dizziness
    fast heartbeat
    headache
    increased hunger
    loss of hearing
    nausea
    nervousness
    nightmares
    rapid growth of normal cells of the thymus (no symptoms)
    seizures
    shakiness
    slurred speech
    thickening of the skin
    unusual tiredness or weakness
    Incidence not known
    Change in the ability to see colors, especially blue or yellow
    cough
    difficult or labored breathing
    difficulty with swallowing
    hives or welts
    itching
    itching or hives at the injection site
    large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
    limp
    pain in the hip or knee
    puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
    redness of the skin
    shortness of breath
    skin rash
    tightness in the chest
    vomiting
    wheezing
    If any of the following symptoms of overdose occur while taking mecasermin, get emergency help immediately:

    Symptoms of overdose
    Anxiety
    arm or leg pain
    backache
    changes in vision
    excessive sweating
    extreme weakness
    frequent urination
    increase in hands and feet size
    increased thirst
    increased volume of pale, diluted urine
    joint pain
    stop in menstruation
    Some of the side effects that can occur with mecasermin may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common
    Abnormal response of the tympanic membrane to air pressure
    difficulty with moving
    difficulty with swallowing
    ear pain
    earache
    large, flat, blue or purplish patches in the skin
    muffled hearing
    muscle pain or stiffness
    redness or swelling in the ear
    sense of fullness in the ear
    snoring
    sore throat
    voice changing
  • (subcutaneous solution)