Isocarboxazid is a monoamine oxidase inhibitor (MAOI) that works by increasing the levels of certain chemicals in the brain.

Isocarboxazid is used to treat symptoms of depression that may include anxiety, panic, or phobias. Isocarboxazid is usually given after other antidepressants have been tried without successful treatment of symptoms.

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  • Marplan
  • Less common
    Burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
    chills
    cold sweats
    confusion
    difficult urination
    dizziness, faintness, or lightheadedness when getting up from lying or sitting position
    fainting
    fast, irregular, pounding, or racing heartbeat or pulse
    fear or nervousness
    heavy feeling
    increased need to urinate
    passing urine more often
    restlessness
    shakiness in the legs, arms, hands, or feet
    sudden jerky movements of the body
    sweating
    trembling or shaking of the hands or feet
    trouble sitting still
    Incidence not known
    Agitation
    burning while urinating
    change in consciousness
    decrease in frequency of urination
    decrease in urine volume
    decreased urine output
    depression
    difficulty in passing urine (dribbling)
    dizziness
    false or unusual sense of well-being
    headache
    hostility
    irritability
    loss of bladder control
    loss of consciousness
    muscle twitching
    nausea
    need to keep moving
    numbness or tingling of the hands, feet, or face
    rapid weight gain
    seeing, hearing, or feeling things that are not there
    seizures
    shakiness and unsteady walk
    stupor
    swelling of the face, ankles, or hands
    unsteadiness, trembling, or other problems with muscle control or coordination
    unusual tiredness or weakness
    Some of the side effects that can occur with isocarboxazid may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common
    Constipation
    dry mouth
    Less common
    Decreased interest in sexual intercourse
    drowsiness
    inability to have or keep an erection
    loss in sexual ability, desire, drive, or performance
    relaxed and calm
    sleepiness
    sleeplessness
    trouble sleeping
    unable to sleep
    unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
    Incidence not known
    Black tongue
    blurred vision
    change in vision
    impaired vision
    increased sensitivity of the skin to sunlight
    itching
    raised, dark red, wart-like spots on the skin, especially when used on the face
    redness or other discoloration of the skin
    severe sunburn
    skin rash
  • (Isocarboxazid) tablet