Maprotiline is an antidepressant. Maprotiline affects chemicals in the brain that may become unbalanced and cause depression.

Maprotiline is used to treat major depressive disorder, depressive neurosis, and manic-depression illness.

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  • Ludiomil
  • More common
    Skin rash, redness, swelling, or itching
    Less common
    Constipation (severe)
    nausea or vomiting
    shakiness or trembling
    seizures (convulsions)
    unusual excitement
    weight loss
    Rare
    Breast enlargement—in males and females
    confusion (especially in the elderly)
    difficulty in urinating
    fainting
    hallucinations (seeing, hearing, or feeling things that are not there)
    inappropriate secretion of milk—in females
    irregular heartbeat (pounding, racing, skipping)
    sore throat and fever
    swelling of testicles
    yellow eyes or skin
    Symptoms of overdose
    Convulsions (seizures)
    dizziness (severe)
    drowsiness (severe)
    fast or irregular heartbeat
    fever
    muscle stiffness or weakness (severe)
    restlessness or agitation
    trouble in breathing
    vomiting
    Some of the side effects that can occur with maprotiline may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common
    Blurred vision
    decreased sexual ability
    dizziness or lightheadedness (especially in the elderly)
    drowsiness
    dryness of mouth
    headache
    increased or decreased sexual drive
    tiredness or weakness
    Less common
    Constipation (mild)
    diarrhea
    heartburn
    increased appetite and weight gain
    increased sensitivity of skin to sunlight
    increased sweating
    trouble in sleeping
    weight loss
  • (oral tablet)