Lotensin (benazepril) is An antihypertensive drug. ACE stands for Hypertensin changingaccelerator.
Lotensin is employed to treat high force per unit area (hypertension).
Lotensin can also be used for functions unlisted during this medication guide.
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Applies to benazepril: oral tablet
In addition to its needed effects, some unwanted effects may be caused by benazepril (the active ingredient contained in Lotensin). In the event that any of these side effects do occur, they may require medical attention.
You should check with your doctor immediately if any of these side effects occur when taking benazepril:
dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
unusual tiredness or weakness
Incidence not known
Arm, back, or jaw pain
blistering, peeling, or loosening of the skin
bloating or swelling of the face, arms, hands, lower legs, or feet
chest pain or discomfort
fast, irregular, pounding, or racing heartbeat or pulse
feeling of warmth
general feeling of tiredness or weakness
joint or muscle pain
large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
rapid weight gain
red skin lesions, often with a purple center
red, irritated eyes
redness of the face, neck, arms, and occasionally, upper chest
shortness of breath
sores, ulcers, or white spots in the mouth or on the lips
tingling of the hands or feet
unusual weight gain or loss
Some of the side effects that can occur with benazepril may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:
sleepiness or unusual drowsiness
Adults The recommended initial dose for patients not receiving a diuretic is 10 mg once a day. The usual maintenance dosage range is 20-40 mg per day administered as a single dose or in two equally divided doses. A dose of 80 mg gives an increased response, but experience with this dose is limited. The divided regimen was more effective in controlling trough (pre-dosing) blood pressure than the same dose given as a once-daily regimen. Dosage adjustment should be based on measurement of peak (2-6 hours after dosing) and trough responses. If a once-daily regimen does not give adequate trough response, an increase in dosage or divided administration should be considered. If blood pressure is not controlled with Lotensin alone, a diuretic can be added. Total daily doses above 80 mg have not been evaluated. Concomitant administration of Lotensin with potassium supplements, potassium salt substitutes, or potassium-sparing diuretics can lead to increases of serum potassium (see PRECAUTIONS). In patients who are currently being treated with a diuretic, symptomatic hypotension occasionally can occur following the initial dose of Lotensin. To reduce the likelihood of hypotension, the diuretic should, if possible, be discontinued two to three days prior to beginning therapy with Lotensin (see WARNINGS). Then, if blood pressure is not controlled with Lotensin alone, diuretic therapy should be resumed. If the diuretic cannot be discontinued, an initial dose of 5 mg Lotensin should be used to avoid excessive hypotension. Pediatrics In children, doses of Lotensin between 0.1 and 0.6 mg/kg once daily have been studied, and doses greater than 0.1 mg/kg were shown to reduce blood pressure (see Pharmacodynamics). Based on this, the recommended starting dose of Lotensin is 0.2 mg/kg once per day as monotherapy. Doses above 0.6 mg/kg (or in excess of 40 mg daily) have not been studied in pediatric patients. For pediatric patients who cannot swallow tablets, or for whom the calculated dosage (mg/kg) does not correspond to the available tablet strengths for Lotensin, follow the suspension preparation instructions below to administer benazepril HCl as a suspension. Treatment with Lotensin is not advised for children below the age of 6 years (see PRECAUTIONS, Pediatric Use) and in pediatric patients with glomerular filtration rate <30 mL, as there are insufficient data available to support a dosing recommendation in these groups.