Treating severe acne in patients who do not respond to other medicines. It may also be used for other conditions as determined by your doctor.

Isotretinoin is a retinoid. It works by reducing skin oil production, changing the characteristics of the skin oil, and preventing abnormal hardening of the skin.

Submit your review

Create your own review

Average rating:  
 0 reviews
  • Examples include Claravis and Sotret
  • Commonly reported side effects of isotretinoin include pruritus, epistaxis, hypertriglyceridemia, xerosis, cheilitis, increased liver enzymes, increased serum triglycerides, musculoskeletal signs and symptoms, decreased hdl cholesterol, dry nose, xerostomia, and xeroderma. Other side effects include increased serum cholesterol. See below for a comprehensive list of adverse effects.

    For the Consumer
    Applies to isotretinoin: oral capsule, oral capsule liquid filled

    In addition to its needed effects, some unwanted effects may be caused by isotretinoin. In the event that any of these side effects do occur, they may require medical attention.

    You should check with your doctor immediately if any of these side effects occur when taking isotretinoin:

    More common
    Bone or joint pain
    burning, redness, itching, or other signs of eye inflammation
    difficulty moving
    scaling, redness, burning, pain, or other signs of inflammation of the lips
    skin infection or rash
    Abdominal or stomach pain (severe)
    attempts at suicide or thoughts of suicide (usually stops after medicine is stopped)
    back pain
    bleeding or inflammation of the gums
    blurred vision or other changes in vision
    changes in behavior
    decreased vision after sunset or before sunrise (sudden or may continue after medicine is stopped)
    diarrhea (severe)
    headache (severe or continuing)
    mental depression
    nausea and vomiting
    pain or tenderness of the eyes
    pain, tenderness, or stiffness in the muscles (long-term treatment)
    rectal bleeding
    yellow eyes or skin
    Incidence not known
    Black, tarry stools
    bloody cough
    bloody or cloudy urine
    bone pain, tenderness, or aching
    burning or stinging of the skin
    chest pain
    cough or hoarseness
    dark-colored urine
    decrease in height
    difficulty breathing
    difficulty speaking
    difficulty swallowing
    discharge from the eyes
    double vision
    ear pain
    excessive tearing
    fast, irregular, pounding, or racing heartbeat or pulse
    fever with or without chills
    fractures and/or delayed healing
    high blood pressure
    inability to move the arms, legs, or facial muscles
    inability to speak
    inflamed tissue from infection
    irregular yellow patch or lump on the skin
    joint pain, redness, stiffness, or swelling
    lack or slowing of normal growth in children
    loosening of the fingernails
    loss of appetite
    loss of bladder control
    loss or change in hearing
    muscle cramps, spasms, or weakness
    pain in the ribs, arms, or legs
    pain or burning in the throat
    pain or tenderness around the eyes and cheekbones
    painful cold sores or blisters on the lips, nose, eyes, or genitals
    painful or difficult urination
    pains in the chest, groin, or legs, especially calves of the legs
    pains in the stomach, side, or abdomen, possibly radiating to the back
    pale skin
    pinpoint red spots on the skin
    redness or soreness around the fingernails
    redness, soreness, or itching skin
    sensitivity of the eyes to sunlight
    shortness of breath
    skin rash
    sores, ulcers, or white spots on the lips or tongue or inside the mouth
    stuffy or runny nose
    sudden loss of consciousness
    sudden loss of coordination
    sudden onset of severe acne on chest and trunk
    sudden onset of slurred speech
    swelling of the eyelids, face, lips, hands, lower legs, or feet
    swollen, painful or tender lymph glands in the neck, armpit, or groin
    tightness in the chest
    unusual bleeding or bruising
    unusual weight gain or loss
    use of extreme physical or emotional force
    watery or bloody diarrhea
    Some of the side effects that can occur with isotretinoin may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common
    Crusting of the skin
    difficulty in wearing contact lenses (may continue after medicine is stopped)
    dryness of the eyes (may continue after treatment is stopped)
    dryness of the mouth or nose
    dryness or itching of the skin
    headache (mild)
    increased sensitivity of the skin to sunlight
    peeling of the skin on palms of the hands or soles of the feet
    stomach upset
    thinning of the hair (may continue after treatment is stopped)
    Incidence not known
    Abnormal menstruation
    burning, crawling, itching, numbness, prickling, “pins and needles”, or tingling feeling
    changes in fingernails or toenails
    continuing ringing or buzzing, or other unexplained noise in the ears
    darkening of the skin
    hair abnormalities
    hair loss
    increased hair growth, especially on the face
    lightening of normal skin color
    lightening of treated areas of dark skin
    oily skin
    redness of the face
    severe sunburn
    skin rash, encrusted, scaly and oozing
    stomach burning
    trouble sleeping
    unable to sleep
    unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
    unusually warm skin of the face
    voice changes
  • Isotretinoin (oral capsule, compounding powder) Please confirm that the medication forms on the dosage document(s) above are relevant for the specific drug you are interested in.
  • Acne

    Minocycline is a tetracycline antibiotic that fights bacteria in the body. Minocycline is used to treat many different bacterial infections, such as urinary tract infections, respiratory infections, skin infections, severe acne, gonorrhea, tick fever, chlamydia, and others. Minocycline may also be used for purposes not listed in this medication guide.