This drug is used to treat high blood pressure. It is also used to lower the risk of strokes in patients with high blood pressure and an enlarged heart. Lowering high blood pressure helps prevent strokes, heart attacks, and kidney problems. This product contains two medications: losartan and hydrochlorothiazide. Losartan is an angiotensin receptor blocker (ARB) and works by relaxing blood vessels so that blood can flow more easily. Hydrochlorothiazide is a “water pill” (diuretic) that causes you to make more urine, which helps your body get rid of extra salt and water.

Hyzaar contains a combination of hydrochlorothiazide and losartan. Hydrochlorothiazide is a thiazide diuretic (water pill) that helps prevent your body from absorbing too much salt, which can cause fluid retention. Losartan is an angiotensin II receptor antagonist. Losartan keeps blood vessels from narrowing, which lowers blood pressure and improves blood flow. It is used to treat high blood pressure (hypertension). It is also used to lower the risk of stroke in certain people with heart disease.

Hyzaar may also be used for purposes not listed in this medication guide.

Important information
Do not use Hyzaar if you are pregnant. Stop using and tell your doctor right away if you become pregnant.

You should not use Hyzaar if you are unable to urinate, or if you are allergic to penicillin or sulfa drugs.
If you have diabetes, do not use Hyzaar together with any medication that contains aliskiren (Amturnide, Tekturna, Tekamlo, Valturna).

In rare cases, Hyzaar can cause a condition that results in the breakdown of skeletal muscle tissue, leading to kidney failure. Call your doctor right away if you have unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine.

 

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  • Losartan, Hydrochlorothizide
  • Dizziness or lightheadedness may occur as your body adjusts to the medication. If any of these effects persist or worsen, tell your doctor or pharmacist promptly.

    To reduce the risk of dizziness and lightheadedness, get up slowly when rising from a sitting or lying position.

    Remember that your doctor has prescribed this medication because he or she has judged that the benefit to you is greater than the risk of side effects. Many people using this medication do not have serious side effects.
  • losartan potassium 50mg, hydrochlorothiazide 12.5mg