Guanfacine reduces nerve impulses in your heart and blood vessels. Guanfacine works by relaxing blood vessels, which lowers blood pressure and improves blood flow.

Guanfacine is used to treat high blood pressure (hypertension). It is sometimes given together with other blood pressure medications.

Guanfacine is also used to treat attention deficit hyperactivity disorder (ADHD) in children who are at least 6 years old.

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  • Intuniv, Tenex
  • More common
    Blurred vision
    confusion
    dizziness, faintness, or lightheadedness when getting up suddenly from a lying or sitting position
    sweating
    unusual tiredness or weakness
    Less common
    Chest pain or discomfort
    cough
    difficulty with breathing
    fast, slow, or irregular heartbeat
    increased need to urinate
    lightheadedness, dizziness, or fainting
    mental depression
    noisy breathing
    passing urine more often
    pounding heartbeat
    tightness in the chest
    If any of the following symptoms of overdose occur while taking guanfacine, get emergency help immediately:

    Symptoms of overdose
    Dizziness (extreme) or faintness
    unusual tiredness or weakness (severe)
    Some of the side effects that can occur with guanfacine may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common
    Constipation
    dizziness
    drowsiness
    dryness of the mouth
    headache
    irritability
    nausea
    sleepiness or unusual drowsiness
    unusual drowsiness, dullness, tiredness, weakness, or feeling of sluggishness
    upper abdominal or stomach pain
    vomiting
    weight gain
    Less common
    Acid or sour stomach
    belching
    decreased appetite
    decreased sexual ability
    dry, itching, or burning eyes
    heartburn
    indigestion
    lack or loss of strength
    paleness of the skin
    stomach discomfort, upset, or pain
    trouble with sleeping
    After you stop taking this drug, it is possible that you may still experience side effects that need medical attention. If you notice any of the following side effects check with your doctor immediately:

    Anxiety or tenseness
    increased salivation
    nervousness or restlessness
    shaking or trembling of the hands and fingers
    stomach cramps
    sweating
  • (oral tablet, oral tablet, extended release)