Fondaparinux is an anticoagulant that helps prevent the formation of blood clots.

Fondaparinux is used to prevent a type of blood clot called deep vein thrombosis (DVT), which can lead to blood clots in the lungs (pulmonary embolism). A DVT can occur after certain types of surgery.

Fondaparinux is also used together with warfarin (Coumadin, Jantoven) to treat DVT, including pulmonary embolism.

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  • Arixtra, Arixtra 5 mg/dose, Arixtra 7.5 mg/dose, Arixtra 10 mg/dose
  • More common
    Pale skin
    troubled breathing with exertion
    unusual bleeding or bruising
    unusual tiredness or weakness
    Less common
    Black, tarry stools
    bladder pain
    bleeding gums
    blood in the urine or stools
    blurred vision
    chest pain
    chills
    collection of blood under the skin
    confusion
    convulsions
    cough
    decreased or cloudy urine
    deep, dark purple bruise
    difficult, burning, or painful urination
    dizziness
    dry mouth
    fainting or lightheadedness when getting up from a lying or sitting position
    fever
    frequent urge to urinate
    increased thirst
    irregular heartbeat
    itching, pain, redness, or swelling at the injection site
    loss of appetite
    lower back or side pain
    muscle pain or cramps
    nausea or vomiting
    numbness or tingling in the hands, feet, or lips
    pinpoint red spots on the skin
    red, tender, or oozing skin at incision
    shortness of breath
    sore throat
    sores, ulcers, or white spots on the lips or in the mouth
    sudden sweating
    Incidence not known
    Back pain
    bowel or bladder dysfunction
    difficulty with swallowing
    fast heartbeat
    hives, itching, or skin rash
    large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
    leg weakness
    numbness
    paralysis
    puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
    tightness in the chest
    If any of the following symptoms of overdose occur while taking fondaparinux, get emergency help immediately:

    Symptoms of overdose
    Abdominal or stomach pain or swelling
    bruising or purple areas on the skin
    coughing up blood
    decreased alertness
    headache
    joint pain or swelling
    nosebleeds
    Some of the side effects that can occur with fondaparinux may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common
    Difficulty having a bowel movement
    swelling
    trouble sleeping
    Less common
    Acid or sour stomach
    belching
    diarrhea
    heartburn
    indigestion
    pain
    skin blisters
    stomach discomfort, upset, or pain
    tightness in the chest
    unusual changes to site of surgery
    wound drainage, increased
  • (subcutaneous solution)