Exalgo (hydromorphone) is an opioid pain medication. An opioid is usually known as a narcotic.

Exalgo extended-release tablets area unit accustomed treat moderate to severe pain.

Exalgo extended-release tablets area unit for continuous treatment of moderate to severe pain. It’s not to be used on an as-needed basis for pain.

Exalgo might also be used for functions unlisted during this medication guide.

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  • Dilaudid, Exalgo, Hydrostat IR
  • Get emergency medical help if you have any signs of an allergic reaction to Exalgo: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

    Call your doctor at once if you have:

    weak or shallow breathing;
    confusion, feelings of extreme happiness or sadness;
    severe weakness or drowsiness; or
    a light-headed feeling, like you might pass out.
    Hydromorphone is more likely to cause breathing problems in older adults and people who are severely ill, malnourished, or otherwise debilitated.

    Common Exalgo side effects may include:

    constipation, nausea, vomiting, stomach pain;
    dizziness, drowsiness;
    headache, tired feeling;
    feelings of extreme happiness or sadness;
    sweating, mild itching;
    dry mouth; or
    flushing (warmth, redness, or tingly feeling).
  • Patients considered opioid-tolerant are those who are taking at least 60 mg of morphine daily, or at least 30 mg of oral oxycodone daily, or at least 8 mg of oral hydromorphone daily or an equianalgesic dose of another opioid for a week or longer. Initiate the dosing regimen for each patient individually, taking into account the patient's prior analgesic treatment experience and risk factors for addiction, abuse, and misuse . Monitor patients closely for respiratory depression, especially within the first 24 to 72 hours of initiating therapy with EXALGO. EXALGO tablets must be taken whole. Crushing, chewing, or dissolving EXALGO extended-release tablets will result in uncontrolled delivery of hydromorphone and can lead to overdose or death.