Etidronate is in a group of medicines called bisphosphonates (bis FOS fo nayts). It alters the cycle of bone formation and breakdown in the body.

Etidronate is used to treat Paget’s disease, and to treat conditions of irregular bone growth due to hip fracture or spinal cord injury.

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  • Didronel, Didronel I.V.
  • More common
    Bone pain or tenderness (increased, continuing, or returning—in patients with Paget's disease)
    Less common
    Bone fractures, especially of the thigh bone
    Rare
    Abdominal or stomach pain or burning
    bloody, black, or tarry stools
    chest pain
    chills
    cough or hoarseness
    fever
    general feeling of tiredness or weakness
    hives
    lower back or side pain
    noisy breathing
    painful or difficult urination
    pale skin
    skin rash or itching
    sore throat
    sores, ulcers, or white spots on the lips or inside the mouth
    swelling of the arms, legs, face, lips, tongue, or throat
    swollen glands
    tightness in the chest
    unusual bleeding or bruising
    Incidence not known
    Blistering, peeling, loosening of the skin
    bone, joint, or muscle pain that is severe and occasionally disabling
    burning, crawling, itching, numbness, prickling, "pins and needles", or tingling feelings
    difficulty in moving
    difficulty in swallowing
    discouragement
    feeling sad or empty
    heartburn
    heavy jaw feeling
    irritability
    lack of appetite
    large, hive-like swelling on the face, eyelids, lips, tongue, throat, hands, legs, feet, or sex organs
    loosening of a tooth
    loss of interest or pleasure
    loss of memory
    pain or burning in the throat
    pain, swelling, or numbness in the mouth or jaw
    problems with memory
    rash with flat lesions or small raised lesions on the skin
    red irritated eyes
    red skin lesions, often with a purple center
    redness or discoloration of the skin
    seeing, hearing, or feeling things that are not there
    trouble concentrating
    trouble sleeping
    unusual tiredness or weakness
    vomiting
    If any of the following symptoms of overdose occur while taking etidronate, get emergency help immediately:

    Symptoms of overdose
    Abdominal or stomach cramps
    confusion
    convulsions
    difficulty in breathing
    irregular heartbeats
    mood or mental changes
    muscle cramps in the hands, arms, feet, legs, or face
    numbness and tingling around the mouth, fingertips, or feet
    shortness of breath
    tremor
    Some of the side effects that can occur with etidronate may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common - at higher doses
    Diarrhea
    nausea
    Incidence not known
    Burning feeling in the chest or stomach
    hair loss, thinning of hair
    headache
    indigestion
    leg cramps
    stomach upset
    tenderness in the stomach area
  • (oral tablet, intravenous solution)