Epiduo gel contains a combination of adapalene and benzoyl peroxide. Adapalene is similar to vitamin A. It helps the skin renew itself. Benzoyl peroxide has an antibacterial effect. It also has a mild drying effect, which allows excess oils and dirt to be easily washed away from the skin.

Epiduo gel is used to treat acne vulgaris (severe acne) in people who are at least 9 years old.

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  • Epiduo
  • Common side effects of Epiduo include burning sensation of skin, stinging of the skin, desquamation, erythema, and xeroderma. See below for a comprehensive list of adverse effects.

    For the Consumer
    Applies to adapalene / benzoyl peroxide topical: topical application gel/jelly

    In addition to its needed effects, some unwanted effects may be caused by adapalene / benzoyl peroxide topical. In the event that any of these side effects do occur, they may require medical attention.

    You should check with your doctor immediately if any of these side effects occur when taking adapalene / benzoyl peroxide topical:

    More common
    Dryness and peeling of the skin
    flushing or redness of the skin
    unusually warm skin
    Less common
    Blistering, burning, crusting, or flaking of the skin
    burning, itching, redness, skin rash, swelling, or soreness at the application site
    scaling, severe redness, or swelling of the skin
    Incidence not known
    Skin pain
    sunburn
    Some of the side effects that can occur with adapalene / benzoyl peroxide topical may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    Incidence not known
    Burning, dry, or itching eyes
    change in the color of the treated skin
    discharge or excessive tearing
    redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
    skin rash, encrusted, scaly, and oozing
    swelling of the face
  • Epiduo (adapalene and benzoyl peroxide) gel General dosage information for the active ingredients contained in Epiduo: Adapalene / Benzoyl Peroxide Topical (topical gel) Please confirm that the medication forms on the dosage document(s) above are relevant for the specific drug you are interested in.
  • Acne

    Minocycline is a tetracycline antibiotic that fights bacteria in the body. Minocycline is used to treat many different bacterial infections, such as urinary tract infections, respiratory infections, skin infections, severe acne, gonorrhea, tick fever, chlamydia, and others. Minocycline may also be used for purposes not listed in this medication guide.