Eloxatin (oxaliplatin) may be a cancer drugs that interferes with the expansion and unfold of cancer cells within thebody.
Eloxatin is employed in conjunction with different cancer medications to treat colon and body part cancer.
Eloxatin can also be used for functions ex-directory during this medication guide.
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Eloxatin can cause a severe or life-threatening allergic reaction. Some people receiving a Eloxatin injection have had a reaction to the infusion within minutes after the medicine is injected into the vein. Tell your caregiver right away if you feel dizzy, short of breath, confused, sweaty, itchy, or have diarrhea, chest pain, warmth or redness in your face, or feel like you might pass out.
Get emergency medical help if you have signs of an allergic reaction to Eloxatin: hives; difficult breathing; swelling of your face, lips, tongue, or throat.
Call your doctor at once if you have:
increased sensitivity to cold temperatures and cold objects;
numbness, tingling, or burning pain that interferes with daily activities;
severe or ongoing diarrhea or vomiting;
confusion, change in mental status, vision problems, seizure (convulsions);
pain or burning when you urinate;
easy bruising, unusual bleeding (nosebleeds, bleeding gums);
sudden chest pain or discomfort, wheezing, dry cough, feeling short of breath;
pain, redness, swelling, or skin changes where the injection was given;
dehydration symptoms - feeling very thirsty or hot, being unable to urinate, heavy sweating, or hot and dry skin;
heart problems - headache with chest pain and severe dizziness, fainting, fast or pounding heartbeats;
liver problems - nausea, upper stomach pain, itching, tiredness, loss of appetite, dark urine, clay-colored stools, jaundice (yellowing of the skin or eyes);
muscle problems - unexplained muscle pain, tenderness, or weakness especially if you also have fever, unusual tiredness, and dark colored urine;
nerve pain - jaw or chest tightness, eye pain, strange feeling in your tongue, problems with speech or swallowing; or
signs of infection - fever, chills, sore throat, mouth and throat ulcers, pain when swallowing, cough with mucus.
Common Eloxatin side effects may include:
nausea, vomiting, diarrhea;
numbness or tingling;
infections, unusual bleeding;
abnormal liver function tests;
mouth sores; or
Usual Adult Dose for Colorectal Cancer: Day 1: Eloxatin 85 mg/m2 and leucovorin 200 mg/m2 intravenously over 120 minutes, followed by fluorouracil 400 mg/m2 over 2 to 4 minutes, followed by fluorouracil 600 mg/m2 as a 22 hour infusion. Day 2: Leucovorin 200 mg/m2 intravenously over 120 minutes, followed by fluorouracil 400 mg/m2 over 2 to 4 minutes, followed by fluorouracil 600 mg/m2 as a 22 hour infusion. The cycle is repeated every 2 weeks.