Atropine obstructs the activity of synthetic called acetylcholine (ah see til KO leen), which may exist in abnormal states in the body after a harming. Atropine additionally invigorates the heart and diminishes the discharges of the nose, mouth, and lungs to enhance relaxing.

Pralidoxime switches muscle shortcoming or loss of motion brought on by a toxic substance or nerve operator.

The blend of atropine and pralidoxime is utilized as a remedy to treat harming by a pesticide (creepy crawly shower) or a compound that meddles with the focal sensory system, for example, nerve gas.

This solution is not powerful as an antitoxin for a wide range of pesticide poisonings. You may require solutions or extra medications.

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  • DuoDote
  • Get emergency medical help if you have any of these signs of an allergic reaction: hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

    Tell your caregivers at once if you have a serious side effect such as:

    pounding heartbeats or fluttering in your chest;
    painful or difficult urination;
    trouble swallowing;
    feeling like you might pass out;
    loss of movement in any part of your body;
    slow heart rate, weak pulse, fainting, slow breathing (breathing may stop); or
    chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling.
    Less serious side effects may include:

    dry mouth, dry nose, dry skin;
    dry eyes, blurred vision;
    increased sensitivity of your eyes to light;
    dizziness, drowsiness;
    muscle weakness;
    constipation, stomach pain, bloating, nausea, vomiting;
    loss of interest in sex, impotence; or
    mild skin rash.
  • Three (3) DuoDote Auto-Injectors should be available for use in each patient (including emergency medical services personnel) at risk for organophosphorous poisoning; one (1) for mild symptoms plus two (2) more for severe symptoms as described below. Each DuoDote Auto-Injector delivers atropine 2.1 mg plus pralidoxime chloride 600 mg.