Dornase alfa is a synthetic protein that breaks down excess DNA in the pulmonary secretions of people with cystic fibrosis.

Dornase alfa is used to improve lung function in people with cystic fibrosis by thinning pulmonary secretions and reducing the risk of respiratory tract infections.

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  • Pulmozyme
  • More common
    Body aches or pain
    chest pain
    congestion
    cough
    dryness or soreness of the throat
    fever
    hoarseness
    runny nose
    tender, swollen glands in the neck
    trouble breathing
    trouble swallowing
    voice changes
    Severity: Minor
    Some of the side effects that can occur with dornase alfa may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

    More common
    Acid or sour stomach
    belching
    heartburn
    indigestion
    rash
    sneezing
    stomach discomfort, upset, or pain
    stuffy nose
    Less common
    Burning, dry, or itching eyes
    discharge or excessive tearing
    redness, pain, or swelling of the eye, eyelid, or inner lining of the eyelid
  • (inhalation solution)